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Combined treatment with flap amputation, phototherapeutic keratectomy, and collagen crosslinking in severe intractable post-LASIK atypical mycobacterial infection with corneal melt.
J Cataract Refract Surg. 2012 Apr; 38(4):713-5.JC

Abstract

A 23-year-old woman was referred for management of intractable post-laser in situ keratomileusis (LASIK) keratitis due to atypical mycobacteria in the left eye. Corrected distance visual acuity was 20/20 in the right eye and counting fingers at 3 meters in the left eye. Slitlamp examination revealed multiple infiltrates in the flap interface and severe corneal stromal melting with thinning. Despite maximum antibiotic therapy for 7 days, the keratitis continued to worsen. A penetrating keratoplasty (PKP) was scheduled. While waiting for a corneal graft, corneal collagen crosslinking (CXL) with riboflavin and ultraviolet-A was proposed as an alternative treatment. Flap amputation and limited phototherapeutic keratotomy (PTK) (10 μm) were also performed. One week postoperatively, all infiltrates and stromal edema had resolved. At 3 months, the uncorrected distance visual acuity improved to 20/35. Corneal crosslinking after flap amputation and limited PTK was an effective treatment for severe intractable post-LASIK keratitis with corneal melting and obviated PKP.

Authors+Show Affiliations

Institute of Vision and Optics, University of Crete, Crete, Greece. kymionis@med.uoc.grNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22365579

Citation

Kymionis, George D., et al. "Combined Treatment With Flap Amputation, Phototherapeutic Keratectomy, and Collagen Crosslinking in Severe Intractable post-LASIK Atypical Mycobacterial Infection With Corneal Melt." Journal of Cataract and Refractive Surgery, vol. 38, no. 4, 2012, pp. 713-5.
Kymionis GD, Kankariya VP, Kontadakis GA. Combined treatment with flap amputation, phototherapeutic keratectomy, and collagen crosslinking in severe intractable post-LASIK atypical mycobacterial infection with corneal melt. J Cataract Refract Surg. 2012;38(4):713-5.
Kymionis, G. D., Kankariya, V. P., & Kontadakis, G. A. (2012). Combined treatment with flap amputation, phototherapeutic keratectomy, and collagen crosslinking in severe intractable post-LASIK atypical mycobacterial infection with corneal melt. Journal of Cataract and Refractive Surgery, 38(4), 713-5. https://doi.org/10.1016/j.jcrs.2012.01.009
Kymionis GD, Kankariya VP, Kontadakis GA. Combined Treatment With Flap Amputation, Phototherapeutic Keratectomy, and Collagen Crosslinking in Severe Intractable post-LASIK Atypical Mycobacterial Infection With Corneal Melt. J Cataract Refract Surg. 2012;38(4):713-5. PubMed PMID: 22365579.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combined treatment with flap amputation, phototherapeutic keratectomy, and collagen crosslinking in severe intractable post-LASIK atypical mycobacterial infection with corneal melt. AU - Kymionis,George D, AU - Kankariya,Vardhaman P, AU - Kontadakis,Georgios A, Y1 - 2012/02/23/ PY - 2011/07/13/received PY - 2011/09/16/revised PY - 2011/09/19/accepted PY - 2012/2/28/entrez PY - 2012/3/1/pubmed PY - 2012/5/31/medline SP - 713 EP - 5 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 38 IS - 4 N2 - A 23-year-old woman was referred for management of intractable post-laser in situ keratomileusis (LASIK) keratitis due to atypical mycobacteria in the left eye. Corrected distance visual acuity was 20/20 in the right eye and counting fingers at 3 meters in the left eye. Slitlamp examination revealed multiple infiltrates in the flap interface and severe corneal stromal melting with thinning. Despite maximum antibiotic therapy for 7 days, the keratitis continued to worsen. A penetrating keratoplasty (PKP) was scheduled. While waiting for a corneal graft, corneal collagen crosslinking (CXL) with riboflavin and ultraviolet-A was proposed as an alternative treatment. Flap amputation and limited phototherapeutic keratotomy (PTK) (10 μm) were also performed. One week postoperatively, all infiltrates and stromal edema had resolved. At 3 months, the uncorrected distance visual acuity improved to 20/35. Corneal crosslinking after flap amputation and limited PTK was an effective treatment for severe intractable post-LASIK keratitis with corneal melting and obviated PKP. SN - 1873-4502 UR - https://www.unboundmedicine.com/medline/citation/22365579/Combined_treatment_with_flap_amputation_phototherapeutic_keratectomy_and_collagen_crosslinking_in_severe_intractable_post_LASIK_atypical_mycobacterial_infection_with_corneal_melt_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0886-3350(12)00014-4 DB - PRIME DP - Unbound Medicine ER -