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The total artificial heart for biventricular heart failure and beyond.
Curr Opin Cardiol. 2012 May; 27(3):301-7.CO

Abstract

PURPOSE OF REVIEW

Treatment options for late-stage biventricular heart failure are limited but include medical therapy with intravenous inotropes, biventricular assist devices (Bi-VADs) and the total artificial heart (TAH). In this manuscript, we review the indications, surgical techniques and outcomes for the TAH.

RECENT FINDINGS

The TAH offers biventricular replacement, rather than 'assistance', as the device is placed orthotopically after excision of the entire ventricular myocardium and all four native valves. In contrast to patients with Bi-VADs, patients with the TAH have no postoperative inotrope requirements, arrhythmias or inflow/outflow cannulae-related complications. Additionally, patients participate in rehabilitation early after device placement and the development of a portable drive may facilitate hospital discharge in the USA. Furthermore, total heart replacement may be ideal for heart failure associated with unique anatomical and mechanical complications.

SUMMARY

The TAH is an effective therapeutic option for the treatment of patients dying of heart failure who may not be suitable candidates for left ventricular assist devices.

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Authors+Show Affiliations

Kasirajan V
Division of Cardiothoracic Surgery, Virginia Commonwealth University, Richmond, Virginia 23298-0204, USA. vkasirajan@mcvh-vcu.edu
Tang DG
No affiliation info available
Katlaps GJ
No affiliation info available
Shah KB
No affiliation info available

MeSH

FemaleHeart FailureHeart VentriclesHeart, ArtificialHemodynamicsHumansMaleMiddle AgedPhysical Therapy Modalities

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22382500

Citation

Kasirajan, Vigneshwar, et al. "The Total Artificial Heart for Biventricular Heart Failure and Beyond." Current Opinion in Cardiology, vol. 27, no. 3, 2012, pp. 301-7.
Kasirajan V, Tang DG, Katlaps GJ, et al. The total artificial heart for biventricular heart failure and beyond. Curr Opin Cardiol. 2012;27(3):301-7.
Kasirajan, V., Tang, D. G., Katlaps, G. J., & Shah, K. B. (2012). The total artificial heart for biventricular heart failure and beyond. Current Opinion in Cardiology, 27(3), 301-7. https://doi.org/10.1097/HCO.0b013e32835220c9
Kasirajan V, et al. The Total Artificial Heart for Biventricular Heart Failure and Beyond. Curr Opin Cardiol. 2012;27(3):301-7. PubMed PMID: 22382500.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The total artificial heart for biventricular heart failure and beyond. AU - Kasirajan,Vigneshwar, AU - Tang,Daniel G, AU - Katlaps,Gundars J, AU - Shah,Keyur B, PY - 2012/3/3/entrez PY - 2012/3/3/pubmed PY - 2012/8/22/medline SP - 301 EP - 7 JF - Current opinion in cardiology JO - Curr Opin Cardiol VL - 27 IS - 3 N2 - PURPOSE OF REVIEW: Treatment options for late-stage biventricular heart failure are limited but include medical therapy with intravenous inotropes, biventricular assist devices (Bi-VADs) and the total artificial heart (TAH). In this manuscript, we review the indications, surgical techniques and outcomes for the TAH. RECENT FINDINGS: The TAH offers biventricular replacement, rather than 'assistance', as the device is placed orthotopically after excision of the entire ventricular myocardium and all four native valves. In contrast to patients with Bi-VADs, patients with the TAH have no postoperative inotrope requirements, arrhythmias or inflow/outflow cannulae-related complications. Additionally, patients participate in rehabilitation early after device placement and the development of a portable drive may facilitate hospital discharge in the USA. Furthermore, total heart replacement may be ideal for heart failure associated with unique anatomical and mechanical complications. SUMMARY: The TAH is an effective therapeutic option for the treatment of patients dying of heart failure who may not be suitable candidates for left ventricular assist devices. SN - 1531-7080 UR - https://www.unboundmedicine.com/medline/citation/22382500/The_total_artificial_heart_for_biventricular_heart_failure_and_beyond_ L2 - https://doi.org/10.1097/HCO.0b013e32835220c9 DB - PRIME DP - Unbound Medicine ER -