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[A cohort investigation of the allergen and pathogenesis in the patients with allergic rhinitis from three hospital of Guangdong Province].

Abstract

OBJECTIVE

To study the pathogenesis of the patients with allergic rhinitis diagnosed by Skin Prick Test (SPT), especially about the epidemiologic data of the involved allergens.

METHOD

The data was collected from 958 patients referred to the listed three allergy center and subsequently diagnosed as allergic rhinitis by SPT.

RESULT

The intermittent mild type was more prevalent in male patients (40.5%); comparably the intermittent moderate type in female patients (70.0%); in the infant patients the moderate-severe type dominated (73.7%). The positive results of SPT comprised mainly of Dermatophagoides pteronyssinus (Der. p, 98.3%), Dermatophagoides farinae(Der. f, 96.8%), and Blomia tropicalis (Blot, 73.8%). Only 1.7% of the patients was allergic to single allergen, in contrary ,the majority of patients were allergic to multiple allergens. The positive rate to Der. p and Der. f was reversely increasing with age of the patients; and contrarily the number of positive allergens was increasing along with the age of the patients. The allergy to outdoor allergen was less common, and the positive rate in skin prick test was lower than the previously reported rate in North China ,such as timothy (3.9%), birch (2.7%), ragweed (2.0%), and mugwort (1.2%).

CONCLUSION

Dust Mite is the predominant allergen for patients with allergic rhinitis in Guangdong province; and the positive rate to outdoor allergen is lower than that in North China.

Authors+Show Affiliations

Department of Otorhinolaryngology, the Fifth Affiliated Hospital, SUN Yat-sen University, Zhuhai, 519000, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

22384564

Citation

Hong, Haiyu, et al. "[A Cohort Investigation of the Allergen and Pathogenesis in the Patients With Allergic Rhinitis From Three Hospital of Guangdong Province]." Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery, vol. 25, no. 23, 2011, pp. 1064-7.
Hong H, Fan Y, Yang Q, et al. [A cohort investigation of the allergen and pathogenesis in the patients with allergic rhinitis from three hospital of Guangdong Province]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011;25(23):1064-7.
Hong, H., Fan, Y., Yang, Q., Li, X., Guo, J., & Chen, X. (2011). [A cohort investigation of the allergen and pathogenesis in the patients with allergic rhinitis from three hospital of Guangdong Province]. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery, 25(23), 1064-7.
Hong H, et al. [A Cohort Investigation of the Allergen and Pathogenesis in the Patients With Allergic Rhinitis From Three Hospital of Guangdong Province]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011;25(23):1064-7. PubMed PMID: 22384564.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [A cohort investigation of the allergen and pathogenesis in the patients with allergic rhinitis from three hospital of Guangdong Province]. AU - Hong,Haiyu, AU - Fan,Yunping, AU - Yang,Qintai, AU - Li,Xiaomin, AU - Guo,Jianling, AU - Chen,Xinye, PY - 2012/3/6/entrez PY - 2012/3/6/pubmed PY - 2012/7/31/medline SP - 1064 EP - 7 JF - Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery JO - Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi VL - 25 IS - 23 N2 - OBJECTIVE: To study the pathogenesis of the patients with allergic rhinitis diagnosed by Skin Prick Test (SPT), especially about the epidemiologic data of the involved allergens. METHOD: The data was collected from 958 patients referred to the listed three allergy center and subsequently diagnosed as allergic rhinitis by SPT. RESULT: The intermittent mild type was more prevalent in male patients (40.5%); comparably the intermittent moderate type in female patients (70.0%); in the infant patients the moderate-severe type dominated (73.7%). The positive results of SPT comprised mainly of Dermatophagoides pteronyssinus (Der. p, 98.3%), Dermatophagoides farinae(Der. f, 96.8%), and Blomia tropicalis (Blot, 73.8%). Only 1.7% of the patients was allergic to single allergen, in contrary ,the majority of patients were allergic to multiple allergens. The positive rate to Der. p and Der. f was reversely increasing with age of the patients; and contrarily the number of positive allergens was increasing along with the age of the patients. The allergy to outdoor allergen was less common, and the positive rate in skin prick test was lower than the previously reported rate in North China ,such as timothy (3.9%), birch (2.7%), ragweed (2.0%), and mugwort (1.2%). CONCLUSION: Dust Mite is the predominant allergen for patients with allergic rhinitis in Guangdong province; and the positive rate to outdoor allergen is lower than that in North China. SN - 1001-1781 UR - https://www.unboundmedicine.com/medline/citation/22384564/[A_cohort_investigation_of_the_allergen_and_pathogenesis_in_the_patients_with_allergic_rhinitis_from_three_hospital_of_Guangdong_Province]_ L2 - http://www.diseaseinfosearch.org/result/7665 DB - PRIME DP - Unbound Medicine ER -