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Comparison of oral manifestations with CD4 count in HIV-infected patients.
Indian J Dent Res. 2011 Sep-Oct; 22(5):732.IJ

Abstract

AIM AND OBJECTIVE

This study was carried out with the primary aim of correlating oral changes and general changes of HIV-infected patients with their CD4 count.

MATERIALS AND METHODS

124 patients were selected, and after taking their informed consent, they were subjected to detailed history taking and thorough clinical examination. Specific oral lesions and general physical changes were recorded. Every patient was subjected to laboratory investigation for CD4 count. All these findings were tabulated. The clinical observation and laboratory findings were subjected to critical analysis and correlated. Statistical test, i.e. Student's " t" test, was applied and objective conclusions were drawn.

RESULT

Out of 124 patients, 40 had oral candidiasis, 6 had oral hairy leukoplakia, 12 had periodontal disease, 20 had xerostomia, 30 had melanin pigmentation, while 4 had HSV2, and atypical ulceration. Out of 40 patients with oral candidiasis, 28 patients had CD4 count <200 (group A), 10 patients were in group, B (CD4 count 200-500 cell/mm 3) and 2 patients in group C(CD4 >500 cell/mm 3). Oral hairy leukoplakia occurred in equal proportions in group A and B. These periodontal diseases were more commonly in group B; xerostomia and melanin pigmentation was equally seen in group A and B.

CONCLUSION

Oral candidiasis, oral hairy leukoplakia, linear gingival erythema, necrotizing ulcerative gingivitis, and necrotizing ulcerative periodontitis are specific oral indicators which will definitely suggest to the dental surgeon that the disease is running a rapid downhill course and due to this the oral physician is in a position to raise a suspicion and alert the general physician regarding the declining immune status of patient.

Authors+Show Affiliations

Department of Oral Medicine and Radiology, Nair Hospital Dental College, Mumbai, India.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

22406727

Citation

Sontakke, Subodh Arun, et al. "Comparison of Oral Manifestations With CD4 Count in HIV-infected Patients." Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research, vol. 22, no. 5, 2011, p. 732.
Sontakke SA, Umarji HR, Karjodkar F. Comparison of oral manifestations with CD4 count in HIV-infected patients. Indian J Dent Res. 2011;22(5):732.
Sontakke, S. A., Umarji, H. R., & Karjodkar, F. (2011). Comparison of oral manifestations with CD4 count in HIV-infected patients. Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research, 22(5), 732. https://doi.org/10.4103/0970-9290.93470
Sontakke SA, Umarji HR, Karjodkar F. Comparison of Oral Manifestations With CD4 Count in HIV-infected Patients. Indian J Dent Res. 2011 Sep-Oct;22(5):732. PubMed PMID: 22406727.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of oral manifestations with CD4 count in HIV-infected patients. AU - Sontakke,Subodh Arun, AU - Umarji,H R, AU - Karjodkar,Freny, PY - 2012/3/13/entrez PY - 2012/3/13/pubmed PY - 2012/8/14/medline SP - 732 EP - 732 JF - Indian journal of dental research : official publication of Indian Society for Dental Research JO - Indian J Dent Res VL - 22 IS - 5 N2 - AIM AND OBJECTIVE: This study was carried out with the primary aim of correlating oral changes and general changes of HIV-infected patients with their CD4 count. MATERIALS AND METHODS: 124 patients were selected, and after taking their informed consent, they were subjected to detailed history taking and thorough clinical examination. Specific oral lesions and general physical changes were recorded. Every patient was subjected to laboratory investigation for CD4 count. All these findings were tabulated. The clinical observation and laboratory findings were subjected to critical analysis and correlated. Statistical test, i.e. Student's " t" test, was applied and objective conclusions were drawn. RESULT: Out of 124 patients, 40 had oral candidiasis, 6 had oral hairy leukoplakia, 12 had periodontal disease, 20 had xerostomia, 30 had melanin pigmentation, while 4 had HSV2, and atypical ulceration. Out of 40 patients with oral candidiasis, 28 patients had CD4 count <200 (group A), 10 patients were in group, B (CD4 count 200-500 cell/mm 3) and 2 patients in group C(CD4 >500 cell/mm 3). Oral hairy leukoplakia occurred in equal proportions in group A and B. These periodontal diseases were more commonly in group B; xerostomia and melanin pigmentation was equally seen in group A and B. CONCLUSION: Oral candidiasis, oral hairy leukoplakia, linear gingival erythema, necrotizing ulcerative gingivitis, and necrotizing ulcerative periodontitis are specific oral indicators which will definitely suggest to the dental surgeon that the disease is running a rapid downhill course and due to this the oral physician is in a position to raise a suspicion and alert the general physician regarding the declining immune status of patient. SN - 1998-3603 UR - https://www.unboundmedicine.com/medline/citation/22406727/Comparison_of_oral_manifestations_with_CD4_count_in_HIV_infected_patients_ L2 - http://www.ijdr.in/article.asp?issn=0970-9290;year=2011;volume=22;issue=5;spage=732;epage=732;aulast=Sontakke DB - PRIME DP - Unbound Medicine ER -