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Flavonol content in the water extract of the mulberry (Morus alba L.) leaf and their antioxidant capacities.
J Food Sci. 2011 Aug; 76(6):C869-73.JF

Abstract

The biological activities of the mulberry (Morus alba L.) leaf have been attributed to its flavonoid content. The water extract of the mulberry leaf (WEML) was prepared by autoclaving at 121 °C for 15 min, and the flavonol content of the WEML was determined by HPLC The WEML contained 4 flavonols in the following order: quercetin-3-β-D-glucose (QT-G) > quercetin-3-O-glucose-6″-acetate (QT-GA) > rutin (RT) > quercetin (QT). In the oxygen radical absorbance capacity (ORAC) assay, QT had the highest peroxyl radical-scavenging capacity and a similar hydroxyl radical-scavenging capacity as its glycosides (QT-G, QT-GA, and RT). QT exhibited a stronger cellular antioxidant capacity (CAC) against 2,2'-Azobis(2-amidinopropane) dihydrochloride (AAPH)- and Cu²⁺-induced oxidative stress in HepG2 cells compared to its glycosides, indicating that the intracellular antioxidant capacity of QT and its glycosides may depend upon both the permeability across the cell membrane and the peroxyl or hydroxyl radical-scavenging capacity.

PRACTICAL APPLICATION

The information presented might be used for developing mulberry leaf-based functional foods.

Authors+Show Affiliations

Dept. of Food and Nutrition, Hannam Univ., 461-6 Jeonmindong Yuseonggu, Daejeon 305-811, Republic of Korea.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22417484

Citation

Kim, Gyo-Nam, and Hae-Dong Jang. "Flavonol Content in the Water Extract of the Mulberry (Morus Alba L.) Leaf and Their Antioxidant Capacities." Journal of Food Science, vol. 76, no. 6, 2011, pp. C869-73.
Kim GN, Jang HD. Flavonol content in the water extract of the mulberry (Morus alba L.) leaf and their antioxidant capacities. J Food Sci. 2011;76(6):C869-73.
Kim, G. N., & Jang, H. D. (2011). Flavonol content in the water extract of the mulberry (Morus alba L.) leaf and their antioxidant capacities. Journal of Food Science, 76(6), C869-73. https://doi.org/10.1111/j.1750-3841.2011.02262.x
Kim GN, Jang HD. Flavonol Content in the Water Extract of the Mulberry (Morus Alba L.) Leaf and Their Antioxidant Capacities. J Food Sci. 2011;76(6):C869-73. PubMed PMID: 22417484.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Flavonol content in the water extract of the mulberry (Morus alba L.) leaf and their antioxidant capacities. AU - Kim,Gyo-Nam, AU - Jang,Hae-Dong, PY - 2012/3/16/entrez PY - 2012/3/16/pubmed PY - 2012/8/17/medline SP - C869 EP - 73 JF - Journal of food science JO - J Food Sci VL - 76 IS - 6 N2 - UNLABELLED: The biological activities of the mulberry (Morus alba L.) leaf have been attributed to its flavonoid content. The water extract of the mulberry leaf (WEML) was prepared by autoclaving at 121 °C for 15 min, and the flavonol content of the WEML was determined by HPLC The WEML contained 4 flavonols in the following order: quercetin-3-β-D-glucose (QT-G) > quercetin-3-O-glucose-6″-acetate (QT-GA) > rutin (RT) > quercetin (QT). In the oxygen radical absorbance capacity (ORAC) assay, QT had the highest peroxyl radical-scavenging capacity and a similar hydroxyl radical-scavenging capacity as its glycosides (QT-G, QT-GA, and RT). QT exhibited a stronger cellular antioxidant capacity (CAC) against 2,2'-Azobis(2-amidinopropane) dihydrochloride (AAPH)- and Cu²⁺-induced oxidative stress in HepG2 cells compared to its glycosides, indicating that the intracellular antioxidant capacity of QT and its glycosides may depend upon both the permeability across the cell membrane and the peroxyl or hydroxyl radical-scavenging capacity. PRACTICAL APPLICATION: The information presented might be used for developing mulberry leaf-based functional foods. SN - 1750-3841 UR - https://www.unboundmedicine.com/medline/citation/22417484/Flavonol_content_in_the_water_extract_of_the_mulberry__Morus_alba_L___leaf_and_their_antioxidant_capacities_ L2 - https://doi.org/10.1111/j.1750-3841.2011.02262.x DB - PRIME DP - Unbound Medicine ER -