Tags

Type your tag names separated by a space and hit enter

Sputnik, a virophage infecting the viral domain of life.
Adv Virus Res. 2012; 82:63-89.AV

Abstract

This chapter discusses the astonishing discovery of the Sputnik virophage, a new virus infecting giant viruses of the genera Mimivirus and Mamavirus. While other virophages have also since been described, this chapter focuses mainly on Sputnik, which is the best described. We detail the general properties of the virophage life cycle, as well as its hosts, genomic characteristics, ecology, and origin. In addition to genetic, phylogenetic, and structural evidence, the existence of virophages has deeply altered our view of the tripartite division of life to include the addition of a fourth domain constituted of the nucleocytoplasmic large DNA viruses, an important point that is discussed.

Links

Publisher Full Text

Authors+Show Affiliations

Desnues C
URMITE, Centre National de la Recherche Scientifique UMR IRD 6236, Faculté de Médecine, Aix-Marseille Université, Marseille, France.
Boyer M
No affiliation info available
Raoult D
No affiliation info available

MeSH

AcanthamoebaAnimalsDNA VirusesDNA, ViralGene ExpressionGenome, ViralMimiviridaePhylogenyViral ProteinsVirionVirus InternalizationVirus Replication

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

22420851

Citation

Desnues, Christelle, et al. "Sputnik, a Virophage Infecting the Viral Domain of Life." Advances in Virus Research, vol. 82, 2012, pp. 63-89.
Desnues C, Boyer M, Raoult D. Sputnik, a virophage infecting the viral domain of life. Adv Virus Res. 2012;82:63-89.
Desnues, C., Boyer, M., & Raoult, D. (2012). Sputnik, a virophage infecting the viral domain of life. Advances in Virus Research, 82, 63-89. https://doi.org/10.1016/B978-0-12-394621-8.00013-3
Desnues C, Boyer M, Raoult D. Sputnik, a Virophage Infecting the Viral Domain of Life. Adv Virus Res. 2012;82:63-89. PubMed PMID: 22420851.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sputnik, a virophage infecting the viral domain of life. AU - Desnues,Christelle, AU - Boyer,Mickaël, AU - Raoult,Didier, PY - 2012/3/17/entrez PY - 2012/3/17/pubmed PY - 2013/6/20/medline SP - 63 EP - 89 JF - Advances in virus research JO - Adv Virus Res VL - 82 N2 - This chapter discusses the astonishing discovery of the Sputnik virophage, a new virus infecting giant viruses of the genera Mimivirus and Mamavirus. While other virophages have also since been described, this chapter focuses mainly on Sputnik, which is the best described. We detail the general properties of the virophage life cycle, as well as its hosts, genomic characteristics, ecology, and origin. In addition to genetic, phylogenetic, and structural evidence, the existence of virophages has deeply altered our view of the tripartite division of life to include the addition of a fourth domain constituted of the nucleocytoplasmic large DNA viruses, an important point that is discussed. SN - 1557-8399 UR - https://www.unboundmedicine.com/medline/citation/22420851/Sputnik_a_virophage_infecting_the_viral_domain_of_life_ L2 - https://linkinghub.elsevier.com/retrieve/pii/B978-0-12-394621-8.00013-3 DB - PRIME DP - Unbound Medicine ER -