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Risk of asthma and allergic outcomes in the offspring in relation to maternal food consumption during pregnancy: a Finnish birth cohort study.
Pediatr Allergy Immunol 2012; 23(2):186-94PA

Abstract

BACKGROUND

Epidemiological and immunological studies suggest that maternal diet during pregnancy might affect the development of allergic diseases in the offspring. The authors set out to study the effect of maternal food consumption during pregnancy on the emergence of the International Study of Asthma and Allergies in Childhood (ISAAC)-based allergic outcomes: asthma, allergic rhinitis, and wheeze by the 5 yr of age.

METHODS

Data from 2441 children at 5 yr of age were analyzed within the Finnish Type 1 Diabetes Prediction and Prevention (DIPP) Nutrition Study, a population-based birth cohort study. Maternal diet was assessed with a validated food frequency questionnaire.

RESULTS

In multiple regression models adjusted for known confounders, low maternal consumption of leafy vegetables (adjusted odds ratio [aOR]: 1.55; 95% CI: 1.21, 1.98), malaceous fruits (aOR: 1.45; 95% CI: 1.15, 1.84), and chocolate (aOR: 1.36; 95% CI: 1.09, 1.70) were positively associated with the risk of wheeze in children. High maternal consumption of fruit and berry juices was positively associated with the risk of allergic rhinitis (aOR: 1.40; 95% CI: 1.03, 1.90) in children. No associations were observed between maternal food consumption and asthma.

CONCLUSIONS

Development of allergic diseases in preschool children may be influenced by intrauterine exposure to maternal diet.

Authors+Show Affiliations

Division of Nutrition, Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland. maijaliisa.erkkola@helsinki.fiNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22432883

Citation

Erkkola, Maijaliisa, et al. "Risk of Asthma and Allergic Outcomes in the Offspring in Relation to Maternal Food Consumption During Pregnancy: a Finnish Birth Cohort Study." Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology, vol. 23, no. 2, 2012, pp. 186-94.
Erkkola M, Nwaru BI, Kaila M, et al. Risk of asthma and allergic outcomes in the offspring in relation to maternal food consumption during pregnancy: a Finnish birth cohort study. Pediatr Allergy Immunol. 2012;23(2):186-94.
Erkkola, M., Nwaru, B. I., Kaila, M., Kronberg-Kippilä, C., Ilonen, J., Simell, O., ... Virtanen, S. M. (2012). Risk of asthma and allergic outcomes in the offspring in relation to maternal food consumption during pregnancy: a Finnish birth cohort study. Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology, 23(2), pp. 186-94. doi:10.1111/j.1399-3038.2012.01272.x.
Erkkola M, et al. Risk of Asthma and Allergic Outcomes in the Offspring in Relation to Maternal Food Consumption During Pregnancy: a Finnish Birth Cohort Study. Pediatr Allergy Immunol. 2012;23(2):186-94. PubMed PMID: 22432883.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Risk of asthma and allergic outcomes in the offspring in relation to maternal food consumption during pregnancy: a Finnish birth cohort study. AU - Erkkola,Maijaliisa, AU - Nwaru,Bright I, AU - Kaila,Minna, AU - Kronberg-Kippilä,Carina, AU - Ilonen,Jorma, AU - Simell,Olli, AU - Veijola,Riitta, AU - Knip,Mikael, AU - Virtanen,Suvi M, PY - 2012/3/22/entrez PY - 2012/3/22/pubmed PY - 2012/7/21/medline SP - 186 EP - 94 JF - Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology JO - Pediatr Allergy Immunol VL - 23 IS - 2 N2 - BACKGROUND: Epidemiological and immunological studies suggest that maternal diet during pregnancy might affect the development of allergic diseases in the offspring. The authors set out to study the effect of maternal food consumption during pregnancy on the emergence of the International Study of Asthma and Allergies in Childhood (ISAAC)-based allergic outcomes: asthma, allergic rhinitis, and wheeze by the 5 yr of age. METHODS: Data from 2441 children at 5 yr of age were analyzed within the Finnish Type 1 Diabetes Prediction and Prevention (DIPP) Nutrition Study, a population-based birth cohort study. Maternal diet was assessed with a validated food frequency questionnaire. RESULTS: In multiple regression models adjusted for known confounders, low maternal consumption of leafy vegetables (adjusted odds ratio [aOR]: 1.55; 95% CI: 1.21, 1.98), malaceous fruits (aOR: 1.45; 95% CI: 1.15, 1.84), and chocolate (aOR: 1.36; 95% CI: 1.09, 1.70) were positively associated with the risk of wheeze in children. High maternal consumption of fruit and berry juices was positively associated with the risk of allergic rhinitis (aOR: 1.40; 95% CI: 1.03, 1.90) in children. No associations were observed between maternal food consumption and asthma. CONCLUSIONS: Development of allergic diseases in preschool children may be influenced by intrauterine exposure to maternal diet. SN - 1399-3038 UR - https://www.unboundmedicine.com/medline/citation/22432883/Risk_of_asthma_and_allergic_outcomes_in_the_offspring_in_relation_to_maternal_food_consumption_during_pregnancy:_a_Finnish_birth_cohort_study_ L2 - https://doi.org/10.1111/j.1399-3038.2012.01272.x DB - PRIME DP - Unbound Medicine ER -