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Nut consumption and risk of atrial fibrillation in the Physicians' Health Study.
Nutr J 2012; 11:17NJ

Abstract

BACKGROUND

Atrial Fibrillation is highly prevalent in clinical practice affecting approximately 2.3 million people in USA and 4.5 million people in European Union. The aim of the study was to examine the association between nut consumption and incident atrial fibrillation.

METHODS

Prospective cohort of 21,054 male participants of Physicians' Health Study I. Nut consumption was estimated using food frequency questionnaire and incident atrial fibrillation was ascertained through yearly follow-up questionnaires. Cox regression was used to estimate relative risks of atrial fibrillation.

RESULTS

The average age was 54.6 ± 9.5 years (40.7-87.1). During a mean follow up of 20 years (median 24 years), 3,317 cases of atrial fibrillation occurred. The crude incidence rate was 7.6, 7.4, 8.2, 7.9, and 6.8 cases/1000 person-years for people reporting nut consumption of rarely/never, 1-3/month, 1/per week, 2-6/week, and ≥ 7/week, respectively. Multivariable adjusted hazard ratios (95% CI) for incident atrial fibrillation were 1.00 (ref), 1.00 (0.90-1.11), 1.09 (0.97-1.21), 1.07 (0.95-1.21), and 0.91 (0.70-1.17) for nut consumption from the lowest to the highest category of nut consumption (p for trend 0.26). No statistically significant association between nut consumption and atrial fibrillation was found when stratified by body mass index (BMI < 25 vs ≥ 25 kg/m2) or age (< 65 vs. ≥ 65 years).

CONCLUSIONS

Our data did not show an association between nut consumption and incident atrial fibrillation among US male physicians.

Authors+Show Affiliations

Harvard Medical School, Boston, MA, USA. oajaz@yahoo.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

22436091

Citation

Khawaja, O, et al. "Nut Consumption and Risk of Atrial Fibrillation in the Physicians' Health Study." Nutrition Journal, vol. 11, 2012, p. 17.
Khawaja O, Gaziano JM, Djousse L. Nut consumption and risk of atrial fibrillation in the Physicians' Health Study. Nutr J. 2012;11:17.
Khawaja, O., Gaziano, J. M., & Djousse, L. (2012). Nut consumption and risk of atrial fibrillation in the Physicians' Health Study. Nutrition Journal, 11, p. 17. doi:10.1186/1475-2891-11-17.
Khawaja O, Gaziano JM, Djousse L. Nut Consumption and Risk of Atrial Fibrillation in the Physicians' Health Study. Nutr J. 2012 Mar 21;11:17. PubMed PMID: 22436091.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nut consumption and risk of atrial fibrillation in the Physicians' Health Study. AU - Khawaja,O, AU - Gaziano,J M, AU - Djousse,L, Y1 - 2012/03/21/ PY - 2011/09/22/received PY - 2012/03/21/accepted PY - 2012/3/23/entrez PY - 2012/3/23/pubmed PY - 2012/8/24/medline SP - 17 EP - 17 JF - Nutrition journal JO - Nutr J VL - 11 N2 - BACKGROUND: Atrial Fibrillation is highly prevalent in clinical practice affecting approximately 2.3 million people in USA and 4.5 million people in European Union. The aim of the study was to examine the association between nut consumption and incident atrial fibrillation. METHODS: Prospective cohort of 21,054 male participants of Physicians' Health Study I. Nut consumption was estimated using food frequency questionnaire and incident atrial fibrillation was ascertained through yearly follow-up questionnaires. Cox regression was used to estimate relative risks of atrial fibrillation. RESULTS: The average age was 54.6 ± 9.5 years (40.7-87.1). During a mean follow up of 20 years (median 24 years), 3,317 cases of atrial fibrillation occurred. The crude incidence rate was 7.6, 7.4, 8.2, 7.9, and 6.8 cases/1000 person-years for people reporting nut consumption of rarely/never, 1-3/month, 1/per week, 2-6/week, and ≥ 7/week, respectively. Multivariable adjusted hazard ratios (95% CI) for incident atrial fibrillation were 1.00 (ref), 1.00 (0.90-1.11), 1.09 (0.97-1.21), 1.07 (0.95-1.21), and 0.91 (0.70-1.17) for nut consumption from the lowest to the highest category of nut consumption (p for trend 0.26). No statistically significant association between nut consumption and atrial fibrillation was found when stratified by body mass index (BMI < 25 vs ≥ 25 kg/m2) or age (< 65 vs. ≥ 65 years). CONCLUSIONS: Our data did not show an association between nut consumption and incident atrial fibrillation among US male physicians. SN - 1475-2891 UR - https://www.unboundmedicine.com/medline/citation/22436091/Nut_consumption_and_risk_of_atrial_fibrillation_in_the_Physicians'_Health_Study_ L2 - https://nutritionj.biomedcentral.com/articles/10.1186/1475-2891-11-17 DB - PRIME DP - Unbound Medicine ER -