An unusual histologic variant of necrobiotic xanthogranuloma.Am J Dermatopathol. 2012 Apr; 34(2):e22-6.AJ
Abstract
Necrobiotic xanthogranuloma (NXG) usually shows a stereotypical histopathologic presentation. However, few unusual cases have been published. We present a patient with NXG showing exceptional histopathologic features. NXG in our patient presents with exclusively dermal granulomatous inflammation mimicking interstitial granuloma annulare. Not only subcutaneous involvement, but also, evident zones of degenerated collagen, foam cells, and cholesterol clefts were missing. Moreover, the case shows overlaps with recently published granulomatous scleromyxedema. Some common clinical and histopathologic features of NXG and scleromyxedema might be based on shared underlying paraproteinemia.
Links
MeSH
Pub Type(s)
Case Reports
Journal Article
Language
eng
PubMed ID
22441374
Citation
Ziemer, Mirjana, et al. "An Unusual Histologic Variant of Necrobiotic Xanthogranuloma." The American Journal of Dermatopathology, vol. 34, no. 2, 2012, pp. e22-6.
Ziemer M, Norgauer J, Simon JC, et al. An unusual histologic variant of necrobiotic xanthogranuloma. Am J Dermatopathol. 2012;34(2):e22-6.
Ziemer, M., Norgauer, J., Simon, J. C., & Koehler, M. J. (2012). An unusual histologic variant of necrobiotic xanthogranuloma. The American Journal of Dermatopathology, 34(2), e22-6. https://doi.org/10.1097/DAD.0b013e3182222aa8
Ziemer M, et al. An Unusual Histologic Variant of Necrobiotic Xanthogranuloma. Am J Dermatopathol. 2012;34(2):e22-6. PubMed PMID: 22441374.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - An unusual histologic variant of necrobiotic xanthogranuloma.
AU - Ziemer,Mirjana,
AU - Norgauer,Johannes,
AU - Simon,Jan-Christoph,
AU - Koehler,Martin Johannes,
PY - 2012/3/24/entrez
PY - 2012/3/24/pubmed
PY - 2012/7/21/medline
SP - e22
EP - 6
JF - The American Journal of dermatopathology
JO - Am J Dermatopathol
VL - 34
IS - 2
N2 - Necrobiotic xanthogranuloma (NXG) usually shows a stereotypical histopathologic presentation. However, few unusual cases have been published. We present a patient with NXG showing exceptional histopathologic features. NXG in our patient presents with exclusively dermal granulomatous inflammation mimicking interstitial granuloma annulare. Not only subcutaneous involvement, but also, evident zones of degenerated collagen, foam cells, and cholesterol clefts were missing. Moreover, the case shows overlaps with recently published granulomatous scleromyxedema. Some common clinical and histopathologic features of NXG and scleromyxedema might be based on shared underlying paraproteinemia.
SN - 1533-0311
UR - https://www.unboundmedicine.com/medline/citation/22441374/An_unusual_histologic_variant_of_necrobiotic_xanthogranuloma_
L2 - https://doi.org/10.1097/DAD.0b013e3182222aa8
DB - PRIME
DP - Unbound Medicine
ER -