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Nicotinic acetylcholine receptor α7 subunit: a novel therapeutic target for cardiovascular diseases.
Front Med. 2012 Mar; 6(1):35-40.FM

Abstract

Inflammation is important in the pathogenesis and development of cardiovascular diseases. Recent studies show that vagus nerve stimulation inhibits pro-inflammatory cytokine production through "the cholinergic anti-inflammatory pathway," more specifically via the α7 nicotinic acetylcholine receptor (α7nAChR). In the current study, the role of the cholinergic anti-inflammatory pathway during septic shock, hypertension, and myocardial infarction is reviewed, and its possible clinical implications in cardiovascular diseases are discussed.

Authors+Show Affiliations

Department of Pharmacology, Second Military Medical University, Shanghai 200433, China.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22460446

Citation

Liu, Chong, and Dingfeng Su. "Nicotinic Acetylcholine Receptor Α7 Subunit: a Novel Therapeutic Target for Cardiovascular Diseases." Frontiers of Medicine, vol. 6, no. 1, 2012, pp. 35-40.
Liu C, Su D. Nicotinic acetylcholine receptor α7 subunit: a novel therapeutic target for cardiovascular diseases. Front Med. 2012;6(1):35-40.
Liu, C., & Su, D. (2012). Nicotinic acetylcholine receptor α7 subunit: a novel therapeutic target for cardiovascular diseases. Frontiers of Medicine, 6(1), 35-40. https://doi.org/10.1007/s11684-012-0171-0
Liu C, Su D. Nicotinic Acetylcholine Receptor Α7 Subunit: a Novel Therapeutic Target for Cardiovascular Diseases. Front Med. 2012;6(1):35-40. PubMed PMID: 22460446.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nicotinic acetylcholine receptor α7 subunit: a novel therapeutic target for cardiovascular diseases. AU - Liu,Chong, AU - Su,Dingfeng, Y1 - 2012/03/31/ PY - 2011/09/26/received PY - 2011/11/02/accepted PY - 2012/3/31/entrez PY - 2012/3/31/pubmed PY - 2012/8/14/medline SP - 35 EP - 40 JF - Frontiers of medicine JO - Front Med VL - 6 IS - 1 N2 - Inflammation is important in the pathogenesis and development of cardiovascular diseases. Recent studies show that vagus nerve stimulation inhibits pro-inflammatory cytokine production through "the cholinergic anti-inflammatory pathway," more specifically via the α7 nicotinic acetylcholine receptor (α7nAChR). In the current study, the role of the cholinergic anti-inflammatory pathway during septic shock, hypertension, and myocardial infarction is reviewed, and its possible clinical implications in cardiovascular diseases are discussed. SN - 2095-0225 UR - https://www.unboundmedicine.com/medline/citation/22460446/Nicotinic_acetylcholine_receptor_α7_subunit:_a_novel_therapeutic_target_for_cardiovascular_diseases_ L2 - https://dx.doi.org/10.1007/s11684-012-0171-0 DB - PRIME DP - Unbound Medicine ER -