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Sleep disturbances in Parkinson's disease with emphasis on rapid eye movement sleep behavior disorder.
Int J Neurosci. 2012 Aug; 122(8):407-12.IJ

Abstract

Sleep disturbances are common in patients with Parkinson's disease (PD). These disturbances can primarily affect the patient's quality of life and may worsen the symptoms of PD. Among the multiple sleep disturbances in PD patients, there has been a marked growing interest in rapid eye movement (REM) sleep behavior disorder (RBD). This is likely due to the fact that RBD has been proven to precede the motor symptoms of PD by many years. The aim of this article is to examine the sleep disturbances found in PD, with special attention to RBD as a premotor symptom of PD, as well as to assess its proposed related pathophysiology. MEDLINE (1966-March 2010), American Academy of Sleep Medicine's, The International Classification of Sleep Disorders, and current textbooks of sleep medicine were searched for relevant information. Search terms: RBD, sleep disturbances, Parkinson's disease, and pre-motor were used. Excessive daytime sleepiness (EDS), sleep attack, insomnia, restless leg syndrome (RLS), sleep-disordered breathing (SDB), and RBD are sleep disturbances commonly found in the literature related to PD. Sleep benefit has been proven to lessen PD motor symptoms. RBD has been described as a premotor symptom of PD in several prospective, retrospective, and cross-sectional studies. Sleep disturbances in PD can result secondarily to natural disease progression, as a side effect of the medications used in PD, or in result of pre-clinical pathology. Treatment of sleep disturbances in PD patients is crucial, as what is termed as, "sleep benefit effect" has been shown to improve the symptoms of PD.

Authors+Show Affiliations

Department of Neurology, Loma Linda University, Loma Linda, California, CA 92782, USA.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22463496

Citation

Barber, Anthony, and Khashayar Dashtipour. "Sleep Disturbances in Parkinson's Disease With Emphasis On Rapid Eye Movement Sleep Behavior Disorder." The International Journal of Neuroscience, vol. 122, no. 8, 2012, pp. 407-12.
Barber A, Dashtipour K. Sleep disturbances in Parkinson's disease with emphasis on rapid eye movement sleep behavior disorder. Int J Neurosci. 2012;122(8):407-12.
Barber, A., & Dashtipour, K. (2012). Sleep disturbances in Parkinson's disease with emphasis on rapid eye movement sleep behavior disorder. The International Journal of Neuroscience, 122(8), 407-12. https://doi.org/10.3109/00207454.2012.677882
Barber A, Dashtipour K. Sleep Disturbances in Parkinson's Disease With Emphasis On Rapid Eye Movement Sleep Behavior Disorder. Int J Neurosci. 2012;122(8):407-12. PubMed PMID: 22463496.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sleep disturbances in Parkinson's disease with emphasis on rapid eye movement sleep behavior disorder. AU - Barber,Anthony, AU - Dashtipour,Khashayar, Y1 - 2012/05/11/ PY - 2012/4/3/entrez PY - 2012/4/3/pubmed PY - 2012/12/10/medline SP - 407 EP - 12 JF - The International journal of neuroscience JO - Int J Neurosci VL - 122 IS - 8 N2 - Sleep disturbances are common in patients with Parkinson's disease (PD). These disturbances can primarily affect the patient's quality of life and may worsen the symptoms of PD. Among the multiple sleep disturbances in PD patients, there has been a marked growing interest in rapid eye movement (REM) sleep behavior disorder (RBD). This is likely due to the fact that RBD has been proven to precede the motor symptoms of PD by many years. The aim of this article is to examine the sleep disturbances found in PD, with special attention to RBD as a premotor symptom of PD, as well as to assess its proposed related pathophysiology. MEDLINE (1966-March 2010), American Academy of Sleep Medicine's, The International Classification of Sleep Disorders, and current textbooks of sleep medicine were searched for relevant information. Search terms: RBD, sleep disturbances, Parkinson's disease, and pre-motor were used. Excessive daytime sleepiness (EDS), sleep attack, insomnia, restless leg syndrome (RLS), sleep-disordered breathing (SDB), and RBD are sleep disturbances commonly found in the literature related to PD. Sleep benefit has been proven to lessen PD motor symptoms. RBD has been described as a premotor symptom of PD in several prospective, retrospective, and cross-sectional studies. Sleep disturbances in PD can result secondarily to natural disease progression, as a side effect of the medications used in PD, or in result of pre-clinical pathology. Treatment of sleep disturbances in PD patients is crucial, as what is termed as, "sleep benefit effect" has been shown to improve the symptoms of PD. SN - 1563-5279 UR - https://www.unboundmedicine.com/medline/citation/22463496/Sleep_disturbances_in_Parkinson's_disease_with_emphasis_on_rapid_eye_movement_sleep_behavior_disorder_ DB - PRIME DP - Unbound Medicine ER -