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[Preloading with HES 130/0.4 versus normal saline solution to prevent hypotension during spinal anaesthesia for elective caesarean section].
Ann Fr Anesth Reanim. 2012 Jun; 31(6):523-7.AF

Abstract

OBJECTIVE

To evaluate the efficacy of HES 130/0.4 preload compared to normal saline solution for prevention of hypotension during spinal anaesthesia for elective caesarean section.

STUDY DESIGN

Prospective, randomized.

PATIENTS AND METHODS

Sixty ASA I patients scheduled for elective caesarean section were randomized to receive either 1000 mL of normal saline solution preload (Group C) or 500 mL of HES 130/0.4 preload (Group V) within 15 minutes prior to spinal anaesthesia. Spinal anaesthesia techniques and ephedrine administration was standardized in both groups. The primary endpoint was the incidence of maternal hypotension before fetal extraction.

RESULTS

The incidence of hypotension before fetal extraction was significantly lower in group V compared to group C (40% vs 66%, P=0.03). Ephedrine consumption was significantly lower in group V (7.6 ± 13 mg vs 16.4 ± 15 mg). Lowest systolic blood pressure was significantly higher in group V (96 ± 14 vs 85 ± 14 mmHg, P=0.005). Incidence of adverse maternal effects and neonatal consequences were similar in both groups.

CONCLUSION

HES 130/0.4 preload reduced the incidence of hypotension, the duration of longest hypotension, and the need for ephedrine during spinal anaesthesia for elective caesarean section. However, the efficacy of HES 130/0.4 alone in prevention of maternal hypotension during spinal anaesthesia for caesarean section is still insufficient.

Authors+Show Affiliations

Service d'anesthésie-réanimation, centre de maternité et de néonatalogie de Tunis, faculté de médecine de Tunis, université de Tunis El Manar, rue Jabel Lakhdar, La Rabta, 1007 Tunis, Tunisie. mouradbouchnak@yahoo.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Randomized Controlled Trial

Language

fre

PubMed ID

22464164

Citation

Bouchnak, M, et al. "[Preloading With HES 130/0.4 Versus Normal Saline Solution to Prevent Hypotension During Spinal Anaesthesia for Elective Caesarean Section]." Annales Francaises D'anesthesie Et De Reanimation, vol. 31, no. 6, 2012, pp. 523-7.
Bouchnak M, Magouri M, Abassi S, et al. [Preloading with HES 130/0.4 versus normal saline solution to prevent hypotension during spinal anaesthesia for elective caesarean section]. Ann Fr Anesth Reanim. 2012;31(6):523-7.
Bouchnak, M., Magouri, M., Abassi, S., Khemiri, K., Tlili, F., Troudi, H., Trabelsi, H., Jabri, H., Ben Mabrouk, A., Abid, A., & Maghrebi, H. (2012). [Preloading with HES 130/0.4 versus normal saline solution to prevent hypotension during spinal anaesthesia for elective caesarean section]. Annales Francaises D'anesthesie Et De Reanimation, 31(6), 523-7. https://doi.org/10.1016/j.annfar.2012.01.030
Bouchnak M, et al. [Preloading With HES 130/0.4 Versus Normal Saline Solution to Prevent Hypotension During Spinal Anaesthesia for Elective Caesarean Section]. Ann Fr Anesth Reanim. 2012;31(6):523-7. PubMed PMID: 22464164.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Preloading with HES 130/0.4 versus normal saline solution to prevent hypotension during spinal anaesthesia for elective caesarean section]. AU - Bouchnak,M, AU - Magouri,M, AU - Abassi,S, AU - Khemiri,K, AU - Tlili,F, AU - Troudi,H, AU - Trabelsi,H, AU - Jabri,H, AU - Ben Mabrouk,A, AU - Abid,A, AU - Maghrebi,H, Y1 - 2012/03/29/ PY - 2010/11/01/received PY - 2012/01/04/accepted PY - 2012/4/3/entrez PY - 2012/4/3/pubmed PY - 2012/11/14/medline SP - 523 EP - 7 JF - Annales francaises d'anesthesie et de reanimation JO - Ann Fr Anesth Reanim VL - 31 IS - 6 N2 - OBJECTIVE: To evaluate the efficacy of HES 130/0.4 preload compared to normal saline solution for prevention of hypotension during spinal anaesthesia for elective caesarean section. STUDY DESIGN: Prospective, randomized. PATIENTS AND METHODS: Sixty ASA I patients scheduled for elective caesarean section were randomized to receive either 1000 mL of normal saline solution preload (Group C) or 500 mL of HES 130/0.4 preload (Group V) within 15 minutes prior to spinal anaesthesia. Spinal anaesthesia techniques and ephedrine administration was standardized in both groups. The primary endpoint was the incidence of maternal hypotension before fetal extraction. RESULTS: The incidence of hypotension before fetal extraction was significantly lower in group V compared to group C (40% vs 66%, P=0.03). Ephedrine consumption was significantly lower in group V (7.6 ± 13 mg vs 16.4 ± 15 mg). Lowest systolic blood pressure was significantly higher in group V (96 ± 14 vs 85 ± 14 mmHg, P=0.005). Incidence of adverse maternal effects and neonatal consequences were similar in both groups. CONCLUSION: HES 130/0.4 preload reduced the incidence of hypotension, the duration of longest hypotension, and the need for ephedrine during spinal anaesthesia for elective caesarean section. However, the efficacy of HES 130/0.4 alone in prevention of maternal hypotension during spinal anaesthesia for caesarean section is still insufficient. SN - 1769-6623 UR - https://www.unboundmedicine.com/medline/citation/22464164/[Preloading_with_HES_130/0_4_versus_normal_saline_solution_to_prevent_hypotension_during_spinal_anaesthesia_for_elective_caesarean_section]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0750-7658(12)00062-7 DB - PRIME DP - Unbound Medicine ER -