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[Parkinson's disease combined with overactive bladder syndrome treated with acupuncture and medication].

Abstract

OBJECTIVE

To evaluate the therapeutic effect of Parkinson's disease combined with overactive bladder syndrome (GAB) treated with combined therapy of oral administration of Tolterodine with low dose and electroacuponcture.

METHODS

Sixty cases of Parkinson's disease combined with GAB were randomly divided into a combined acupuncture and medication group (group A) and a medication group (group B), 30 cases in each group. In both groups, Madopar basic doses were same, and anticholinergic agents such as Artane were stopped. In group A, Tolterodine was orally taken for 1 mg, twice a day; Baihui (GV 20), Sishengcong (EX-HN 1) and Yintang (EX-HN 3) were punctured with electroacupuncture, once a day. In group B, Tolterodine was orally taken for 2 mg, twice a day. After 6 weeks, the changes of urination and UPDRS III scores were observed, and the adverse reactions were recorded in both groups.

RESULTS

After treatment, the frequency of average urination of 24 hours, frequency of incontinence of 24 hours and average urine volume at a time were obviously improved (all P < 0. 01), of which, the above items in group A were superior to those in group B (all P < 0. 05) the UPDRSIII score in group A was superior to that in group B (P < 0.05). The adverse reactions in group A were less than those in group B.

CONCLUSION

The therapeutic effect of Parkinson' s disease combined with GAB treated with combined therapy of Tolterodine with low dose and electroacupuncture is superior to that of complete dose of Tolterodine with oral administration, with less adverse reactions. And it also can improve the motor symptom of Parkinson's disease patients.

Authors+Show Affiliations

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Acupuncture-Moxibustion and Massage Department, People's Hospital of Yizheng City, Yizheng 211400, Jiangsu Province, China. cyl0514@163.com

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Source

MeSH

Adult
Aged
Benzhydryl Compounds
Combined Modality Therapy
Cresols
Electroacupuncture
Female
Humans
Male
Middle Aged
Parkinson Disease
Phenylpropanolamine
Tolterodine Tartrate
Urinary Bladder, Overactive

Pub Type(s)

English Abstract
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

22471132

Citation

Chen, Yi-Liang', et al. "[Parkinson's Disease Combined With Overactive Bladder Syndrome Treated With Acupuncture and Medication]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 32, no. 3, 2012, pp. 215-8.
Chen YL, Feng WJ, Zhang XL. [Parkinson's disease combined with overactive bladder syndrome treated with acupuncture and medication]. Zhongguo Zhen Jiu. 2012;32(3):215-8.
Chen, Y. L., Feng, W. J., & Zhang, X. L. (2012). [Parkinson's disease combined with overactive bladder syndrome treated with acupuncture and medication]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 32(3), pp. 215-8.
Chen YL, Feng WJ, Zhang XL. [Parkinson's Disease Combined With Overactive Bladder Syndrome Treated With Acupuncture and Medication]. Zhongguo Zhen Jiu. 2012;32(3):215-8. PubMed PMID: 22471132.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Parkinson's disease combined with overactive bladder syndrome treated with acupuncture and medication]. AU - Chen,Yi-Liang', AU - Feng,Wei-Ju, AU - Zhang,Xiao-Li, PY - 2012/4/5/entrez PY - 2012/4/5/pubmed PY - 2012/5/4/medline SP - 215 EP - 8 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 32 IS - 3 N2 - OBJECTIVE: To evaluate the therapeutic effect of Parkinson's disease combined with overactive bladder syndrome (GAB) treated with combined therapy of oral administration of Tolterodine with low dose and electroacuponcture. METHODS: Sixty cases of Parkinson's disease combined with GAB were randomly divided into a combined acupuncture and medication group (group A) and a medication group (group B), 30 cases in each group. In both groups, Madopar basic doses were same, and anticholinergic agents such as Artane were stopped. In group A, Tolterodine was orally taken for 1 mg, twice a day; Baihui (GV 20), Sishengcong (EX-HN 1) and Yintang (EX-HN 3) were punctured with electroacupuncture, once a day. In group B, Tolterodine was orally taken for 2 mg, twice a day. After 6 weeks, the changes of urination and UPDRS III scores were observed, and the adverse reactions were recorded in both groups. RESULTS: After treatment, the frequency of average urination of 24 hours, frequency of incontinence of 24 hours and average urine volume at a time were obviously improved (all P < 0. 01), of which, the above items in group A were superior to those in group B (all P < 0. 05) the UPDRSIII score in group A was superior to that in group B (P < 0.05). The adverse reactions in group A were less than those in group B. CONCLUSION: The therapeutic effect of Parkinson' s disease combined with GAB treated with combined therapy of Tolterodine with low dose and electroacupuncture is superior to that of complete dose of Tolterodine with oral administration, with less adverse reactions. And it also can improve the motor symptom of Parkinson's disease patients. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/22471132/[Parkinson's_disease_combined_with_overactive_bladder_syndrome_treated_with_acupuncture_and_medication]_ L2 - https://medlineplus.gov/overactivebladder.html DB - PRIME DP - Unbound Medicine ER -