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Essential oil from the leaves of Annona vepretorum: chemical composition and bioactivity.
Nat Prod Commun. 2012 Feb; 7(2):265-6.NP

Abstract

The essential oil from the leaves of Annona vepretorun was obtained by hydrodistillation using a Clevenger-type apparatus and analyzed by GC-MS and GC-FID. Eighteen compounds representing 98.1% of the crude essential oil were identified. The major compounds identified were bicyclogermacrene (43.7%), spathulenol (11.4%), alpha-felandrene (10.0%), alpha-pinene (7.1%), (E)-beta-ocimene (6.8%), germacrene D (5.8%), and p-cymene (4.2%). The trypanocidal activity against Trypanosoma cruzi epimastigote forms, as well as, the antimicrobial and antioxidant proprieties was investigated. The essential oil showed a potent trypanocidal activity with IC50 value of 31.9 +/-1.3 microg x mL(-1). For antimicrobial activity, the best result was observed against Candida tropicalis with a MIC value of 100 microg x mL(-1). For antioxidant capacity the essential oil showed weak activity.

Authors+Show Affiliations

Costa EV
Department of Chemistry, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil 49100-000. emmanoelvilaca@yahoo.com.br
Dutra LM
No affiliation info available
Nogueira PC
No affiliation info available
Moraes VR
No affiliation info available
Salvador MJ
No affiliation info available
Ribeiro LH
No affiliation info available
Gadelha FR
No affiliation info available

MeSH

AnnonaAnti-Infective AgentsOils, VolatilePlant LeavesPlant Oils

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22474976

Citation

Costa, Emmanoel Vilaça, et al. "Essential Oil From the Leaves of Annona Vepretorum: Chemical Composition and Bioactivity." Natural Product Communications, vol. 7, no. 2, 2012, pp. 265-6.
Costa EV, Dutra LM, Nogueira PC, et al. Essential oil from the leaves of Annona vepretorum: chemical composition and bioactivity. Nat Prod Commun. 2012;7(2):265-6.
Costa, E. V., Dutra, L. M., Nogueira, P. C., Moraes, V. R., Salvador, M. J., Ribeiro, L. H., & Gadelha, F. R. (2012). Essential oil from the leaves of Annona vepretorum: chemical composition and bioactivity. Natural Product Communications, 7(2), 265-6.
Costa EV, et al. Essential Oil From the Leaves of Annona Vepretorum: Chemical Composition and Bioactivity. Nat Prod Commun. 2012;7(2):265-6. PubMed PMID: 22474976.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Essential oil from the leaves of Annona vepretorum: chemical composition and bioactivity. AU - Costa,Emmanoel Vilaça, AU - Dutra,Lívia Macedo, AU - Nogueira,Paulo Cesar de Lima, AU - Moraes,Valéria Regina de Souza, AU - Salvador,Marcos José, AU - Ribeiro,Luis Henrique Gonzaga, AU - Gadelha,Fernanda Ramos, PY - 2012/4/6/entrez PY - 2012/4/6/pubmed PY - 2012/4/25/medline SP - 265 EP - 6 JF - Natural product communications JO - Nat Prod Commun VL - 7 IS - 2 N2 - The essential oil from the leaves of Annona vepretorun was obtained by hydrodistillation using a Clevenger-type apparatus and analyzed by GC-MS and GC-FID. Eighteen compounds representing 98.1% of the crude essential oil were identified. The major compounds identified were bicyclogermacrene (43.7%), spathulenol (11.4%), alpha-felandrene (10.0%), alpha-pinene (7.1%), (E)-beta-ocimene (6.8%), germacrene D (5.8%), and p-cymene (4.2%). The trypanocidal activity against Trypanosoma cruzi epimastigote forms, as well as, the antimicrobial and antioxidant proprieties was investigated. The essential oil showed a potent trypanocidal activity with IC50 value of 31.9 +/-1.3 microg x mL(-1). For antimicrobial activity, the best result was observed against Candida tropicalis with a MIC value of 100 microg x mL(-1). For antioxidant capacity the essential oil showed weak activity. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/22474976/Essential_oil_from_the_leaves_of_Annona_vepretorum:_chemical_composition_and_bioactivity_ DB - PRIME DP - Unbound Medicine ER -