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Copper in Alzheimer's disease: a meta-analysis of serum, plasma, and cerebrospinal fluid studies.

Abstract

This contribution reviews and corrects data from our previous meta-analysis, which appeared in the Journal of Alzheimer's Disease in 2011 concerning the role of copper in Alzheimer's disease. We repeated the meta-analysis after excluding four of the five studies from our laboratory to avoid possible bias in the result. In addition, we included two studies on serum copper levels in Alzheimer's disease not previously considered. The results indicate higher levels of copper in Alzheimer's disease patients than in controls, confirming our previous conclusion.

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  • Authors

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    Source

    MeSH

    Alzheimer Disease
    Biological Markers
    Copper
    Humans

    Pub Type(s)

    Corrected and Republished Article
    Journal Article
    Meta-Analysis
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    22475798

    Citation

    TY - JOUR T1 - Copper in Alzheimer's disease: a meta-analysis of serum, plasma, and cerebrospinal fluid studies. AU - Ventriglia,Mariacarla, AU - Bucossi,Serena, AU - Panetta,Valentina, AU - Squitti,Rosanna, PY - 2012/4/6/entrez PY - 2012/4/6/pubmed PY - 2013/5/17/medline SP - 981 EP - 4 JF - Journal of Alzheimer's disease : JAD JO - J. Alzheimers Dis. VL - 30 IS - 4 N2 - This contribution reviews and corrects data from our previous meta-analysis, which appeared in the Journal of Alzheimer's Disease in 2011 concerning the role of copper in Alzheimer's disease. We repeated the meta-analysis after excluding four of the five studies from our laboratory to avoid possible bias in the result. In addition, we included two studies on serum copper levels in Alzheimer's disease not previously considered. The results indicate higher levels of copper in Alzheimer's disease patients than in controls, confirming our previous conclusion. SN - 1875-8908 UR - https://www.unboundmedicine.com/medline/citation/22475798/full_citation L2 - http://iospress.metapress.com/openurl.asp?genre=article&issn=1387-2877&volume=30&issue=4&spage=981 ER -