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Reduction of overall Helicobacter pylori colonization levels in the stomach of Mongolian gerbil by Lactobacillus johnsonii La1 (LC1) and its in vitro activities against H. pylori motility and adherence.
Biosci Biotechnol Biochem 2012; 76(4):850-2BB

Abstract

The effects of Lactobacillus johnsonii La1 (LC1) on Helicobacter pylori colonization in the stomach were investigated. H. pylori colonization and gastritis in LC1-inoculated Mongolian gerbils were significantly less intense than those in the control animals. LC1 culture supernatant (>10-kDa fraction) inhibited H. pylori motility and induced bacterial aggregation in human gastric epithelial cells, suggesting the potential of clinical use of LC1 product.

Authors+Show Affiliations

Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22484956

Citation

Isobe, Hirokazu, et al. "Reduction of Overall Helicobacter Pylori Colonization Levels in the Stomach of Mongolian Gerbil By Lactobacillus Johnsonii La1 (LC1) and Its in Vitro Activities Against H. Pylori Motility and Adherence." Bioscience, Biotechnology, and Biochemistry, vol. 76, no. 4, 2012, pp. 850-2.
Isobe H, Nishiyama A, Takano T, et al. Reduction of overall Helicobacter pylori colonization levels in the stomach of Mongolian gerbil by Lactobacillus johnsonii La1 (LC1) and its in vitro activities against H. pylori motility and adherence. Biosci Biotechnol Biochem. 2012;76(4):850-2.
Isobe, H., Nishiyama, A., Takano, T., Higuchi, W., Nakagawa, S., Taneike, I., ... Yamamoto, T. (2012). Reduction of overall Helicobacter pylori colonization levels in the stomach of Mongolian gerbil by Lactobacillus johnsonii La1 (LC1) and its in vitro activities against H. pylori motility and adherence. Bioscience, Biotechnology, and Biochemistry, 76(4), pp. 850-2.
Isobe H, et al. Reduction of Overall Helicobacter Pylori Colonization Levels in the Stomach of Mongolian Gerbil By Lactobacillus Johnsonii La1 (LC1) and Its in Vitro Activities Against H. Pylori Motility and Adherence. Biosci Biotechnol Biochem. 2012;76(4):850-2. PubMed PMID: 22484956.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reduction of overall Helicobacter pylori colonization levels in the stomach of Mongolian gerbil by Lactobacillus johnsonii La1 (LC1) and its in vitro activities against H. pylori motility and adherence. AU - Isobe,Hirokazu, AU - Nishiyama,Akihito, AU - Takano,Tomomi, AU - Higuchi,Wataru, AU - Nakagawa,Saori, AU - Taneike,Ikue, AU - Fukushima,Yoichi, AU - Yamamoto,Tatsuo, Y1 - 2012/04/07/ PY - 2012/4/10/entrez PY - 2012/4/10/pubmed PY - 2012/12/10/medline SP - 850 EP - 2 JF - Bioscience, biotechnology, and biochemistry JO - Biosci. Biotechnol. Biochem. VL - 76 IS - 4 N2 - The effects of Lactobacillus johnsonii La1 (LC1) on Helicobacter pylori colonization in the stomach were investigated. H. pylori colonization and gastritis in LC1-inoculated Mongolian gerbils were significantly less intense than those in the control animals. LC1 culture supernatant (>10-kDa fraction) inhibited H. pylori motility and induced bacterial aggregation in human gastric epithelial cells, suggesting the potential of clinical use of LC1 product. SN - 1347-6947 UR - https://www.unboundmedicine.com/medline/citation/22484956/Reduction_of_overall_Helicobacter_pylori_colonization_levels_in_the_stomach_of_Mongolian_gerbil_by_Lactobacillus_johnsonii_La1__LC1__and_its_in_vitro_activities_against_H__pylori_motility_and_adherence_ L2 - http://joi.jlc.jst.go.jp/JST.JSTAGE/bbb/110921?lang=en&from=PubMed DB - PRIME DP - Unbound Medicine ER -