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A case of Klinefelter's syndrome with type 1 diabetes mellitus.
Chin Med J (Engl) 2012; 125(5):937-40CM

Abstract

Klinefelter’s syndrome (KS) is the most common sex chromosome disease in men. Classical features of the syndrome include a eunuchoidal body habitus, small testes and hypergonadotrophic hypogonadism. There has been an increased risk of diabetes mellitus and autoimmune disease for KS patients. This paper reports a case of KS in association with type 1 diabetes mellitus. The patient was a 21-year-old man, who has been confirmed by absolute insulin deficiency and positive IA-2 autoantibody. The hyperinsulinemic euglycemic clamp test indicated his insulin sensitivity in normal range, and his blood glucose was controlled well by the insulin therapy.

Authors+Show Affiliations

Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, and Department of Endocrinology, China-Japan Friendship Hospital, Beijing 100730, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22490600

Citation

Cai, Xiao-pin, et al. "A Case of Klinefelter's Syndrome With Type 1 Diabetes Mellitus." Chinese Medical Journal, vol. 125, no. 5, 2012, pp. 937-40.
Cai XP, Zhao L, Mao M, et al. A case of Klinefelter's syndrome with type 1 diabetes mellitus. Chin Med J. 2012;125(5):937-40.
Cai, X. P., Zhao, L., Mao, M., Yang, Z. J., Xing, X. Y., & Li, G. W. (2012). A case of Klinefelter's syndrome with type 1 diabetes mellitus. Chinese Medical Journal, 125(5), pp. 937-40.
Cai XP, et al. A Case of Klinefelter's Syndrome With Type 1 Diabetes Mellitus. Chin Med J. 2012;125(5):937-40. PubMed PMID: 22490600.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A case of Klinefelter's syndrome with type 1 diabetes mellitus. AU - Cai,Xiao-pin, AU - Zhao,Li, AU - Mao,Min, AU - Yang,Zhao-jun, AU - Xing,Xiao-yan, AU - Li,Guang-wei, PY - 2012/4/12/entrez PY - 2012/4/12/pubmed PY - 2012/8/4/medline SP - 937 EP - 40 JF - Chinese medical journal JO - Chin. Med. J. VL - 125 IS - 5 N2 - Klinefelter’s syndrome (KS) is the most common sex chromosome disease in men. Classical features of the syndrome include a eunuchoidal body habitus, small testes and hypergonadotrophic hypogonadism. There has been an increased risk of diabetes mellitus and autoimmune disease for KS patients. This paper reports a case of KS in association with type 1 diabetes mellitus. The patient was a 21-year-old man, who has been confirmed by absolute insulin deficiency and positive IA-2 autoantibody. The hyperinsulinemic euglycemic clamp test indicated his insulin sensitivity in normal range, and his blood glucose was controlled well by the insulin therapy. SN - 0366-6999 UR - https://www.unboundmedicine.com/medline/citation/22490600/A_case_of_Klinefelter's_syndrome_with_type_1_diabetes_mellitus_ L2 - http://Insights.ovid.com/pubmed?pmid=22490600 DB - PRIME DP - Unbound Medicine ER -