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Lewy pathology and neurodegeneration in premotor Parkinson's disease.
Mov Disord. 2012 Apr 15; 27(5):597-607.MD

Abstract

The foremost motor manifestations of Parkinson's disease are resting tremor, cogwheel rigidity, hypokinesia/bradykinesia, and postural instability. Epidemiological and clinical data reveal that a wide variety of additional complaints (nonmotor symptoms), also considerably impar patients' quality of life parallel to the chronic-progressive neurodegenerative disorder. This article reviews the neuropathology and anatomy of Lewy pathology-related neurodegeneration in relation to selected nonmotro and prodromal dysfunctions.

Authors+Show Affiliations

Clinical Neuroanatomy Section, Department of Neurology, Center for Biomedical Research, University of Ulm, Ulm, Germany. kelly.del-tredici@uni-ulm.deNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22508278

Citation

Del Tredici, Kelly, and Heiko Braak. "Lewy Pathology and Neurodegeneration in Premotor Parkinson's Disease." Movement Disorders : Official Journal of the Movement Disorder Society, vol. 27, no. 5, 2012, pp. 597-607.
Del Tredici K, Braak H. Lewy pathology and neurodegeneration in premotor Parkinson's disease. Mov Disord. 2012;27(5):597-607.
Del Tredici, K., & Braak, H. (2012). Lewy pathology and neurodegeneration in premotor Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society, 27(5), 597-607. https://doi.org/10.1002/mds.24921
Del Tredici K, Braak H. Lewy Pathology and Neurodegeneration in Premotor Parkinson's Disease. Mov Disord. 2012 Apr 15;27(5):597-607. PubMed PMID: 22508278.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lewy pathology and neurodegeneration in premotor Parkinson's disease. AU - Del Tredici,Kelly, AU - Braak,Heiko, PY - 2012/4/18/entrez PY - 2012/4/18/pubmed PY - 2012/8/24/medline SP - 597 EP - 607 JF - Movement disorders : official journal of the Movement Disorder Society JO - Mov Disord VL - 27 IS - 5 N2 - The foremost motor manifestations of Parkinson's disease are resting tremor, cogwheel rigidity, hypokinesia/bradykinesia, and postural instability. Epidemiological and clinical data reveal that a wide variety of additional complaints (nonmotor symptoms), also considerably impar patients' quality of life parallel to the chronic-progressive neurodegenerative disorder. This article reviews the neuropathology and anatomy of Lewy pathology-related neurodegeneration in relation to selected nonmotro and prodromal dysfunctions. SN - 1531-8257 UR - https://www.unboundmedicine.com/medline/citation/22508278/Lewy_pathology_and_neurodegeneration_in_premotor_Parkinson's_disease_ L2 - https://doi.org/10.1002/mds.24921 DB - PRIME DP - Unbound Medicine ER -