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Traditional Chinese medicine for pressure ulcer: a meta-analysis.
Int Wound J. 2013 Apr; 10(2):221-31.IW

Abstract

To assess the effect of Traditional Chinese Medicine (TCM) [Chinese herbal medicine ointment (CHMO), acupuncture and moxibustion] on pressure ulcer. In this study, we searched MEDLINE, EMBASE, CENTER, CBM, CNKI, WAN FANG and VIP for articles published from database inception up to 4 April 2011. We included randomised controlled trials (RCTs), which compared the effects of TCM with other interventions. We assessed the methodological quality of these trials using Cochrane risk of bias criteria. Ten of 565 potentially relevant trails that enrolled a total of 893 patients met our inclusion criteria. All the included RCTs only used CHMO intervention, because acupuncture and moxibustion trials failed to meet the inclusive criteria. A meta-analysis showed beneficial effects of CHMO for pressure ulcer compared with other treatments on the total effective rate [risk ratio (RR): 1·28; 95% confidence interval (CI): 1·20-1·36; P = 0·53; I(2) = 0%), curative ratio (RR: 2·02; 95% CI: 1·73-2·35; P = 0·11; I(2) = 37%) and inefficiency rate (RR: 0·16; 95% CI: 0·02-0·80; P = 0·84; I(2) = 0%). However, the funnel plot indicated that there was publication bias in this study. The evidence that CHMO is effective for pressure ulcer is encouraging, but due to several caveats, not conclusive. Therefore, more rigorous studies seem warranted.

Authors+Show Affiliations

College of Basic Medical Sciences of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

22512889

Citation

Zhang, Qin-Hong, et al. "Traditional Chinese Medicine for Pressure Ulcer: a Meta-analysis." International Wound Journal, vol. 10, no. 2, 2013, pp. 221-31.
Zhang QH, Sun ZR, Yue JH, et al. Traditional Chinese medicine for pressure ulcer: a meta-analysis. Int Wound J. 2013;10(2):221-31.
Zhang, Q. H., Sun, Z. R., Yue, J. H., Ren, X., Qiu, L. B., Lv, X. L., & Du, W. (2013). Traditional Chinese medicine for pressure ulcer: a meta-analysis. International Wound Journal, 10(2), 221-31. https://doi.org/10.1111/j.1742-481X.2012.00969.x
Zhang QH, et al. Traditional Chinese Medicine for Pressure Ulcer: a Meta-analysis. Int Wound J. 2013;10(2):221-31. PubMed PMID: 22512889.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Traditional Chinese medicine for pressure ulcer: a meta-analysis. AU - Zhang,Qin-Hong, AU - Sun,Zhong-Ren, AU - Yue,Jin-Huan, AU - Ren,Xue, AU - Qiu,Li-Bo, AU - Lv,Xiao-Lin, AU - Du,Wei, Y1 - 2012/04/18/ PY - 2012/4/20/entrez PY - 2012/4/20/pubmed PY - 2013/9/17/medline SP - 221 EP - 31 JF - International wound journal JO - Int Wound J VL - 10 IS - 2 N2 - To assess the effect of Traditional Chinese Medicine (TCM) [Chinese herbal medicine ointment (CHMO), acupuncture and moxibustion] on pressure ulcer. In this study, we searched MEDLINE, EMBASE, CENTER, CBM, CNKI, WAN FANG and VIP for articles published from database inception up to 4 April 2011. We included randomised controlled trials (RCTs), which compared the effects of TCM with other interventions. We assessed the methodological quality of these trials using Cochrane risk of bias criteria. Ten of 565 potentially relevant trails that enrolled a total of 893 patients met our inclusion criteria. All the included RCTs only used CHMO intervention, because acupuncture and moxibustion trials failed to meet the inclusive criteria. A meta-analysis showed beneficial effects of CHMO for pressure ulcer compared with other treatments on the total effective rate [risk ratio (RR): 1·28; 95% confidence interval (CI): 1·20-1·36; P = 0·53; I(2) = 0%), curative ratio (RR: 2·02; 95% CI: 1·73-2·35; P = 0·11; I(2) = 37%) and inefficiency rate (RR: 0·16; 95% CI: 0·02-0·80; P = 0·84; I(2) = 0%). However, the funnel plot indicated that there was publication bias in this study. The evidence that CHMO is effective for pressure ulcer is encouraging, but due to several caveats, not conclusive. Therefore, more rigorous studies seem warranted. SN - 1742-481X UR - https://www.unboundmedicine.com/medline/citation/22512889/Traditional_Chinese_medicine_for_pressure_ulcer:_a_meta_analysis_ L2 - https://doi.org/10.1111/j.1742-481X.2012.00969.x DB - PRIME DP - Unbound Medicine ER -