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Clinical predictors of community-genotype ST72-methicillin-resistant Staphylococcus aureus-SCCmec type IV in patients with community-onset S. aureus infection.
J Antimicrob Chemother 2012; 67(7):1755-9JA

Abstract

OBJECTIVES

Community-genotype methicillin-resistant Staphylococcus aureus (MRSA) clones have emerged in the community worldwide and recently have been spreading into the hospitals. To identify predictors of sequence type 72-MRSA-SCCmec type IV (ST72-MRSA-IV) in patients with community-onset (CO) S. aureus infection, a case-control study was conducted among CO S. aureus infections, including healthcare-associated infections.

METHODS

Eighty-four patients with CO infections caused by ST72-MRSA-IV strains in Korea between 2007 and 2009 were selected as cases. Members of the control group were those with CO methicillin-susceptible S. aureus infections and they were matched by the admission date in a 1 : 1 ratio.

RESULTS

The most common type of infection was skin and soft tissue infection in both groups (48.8% versus 52.4%), followed by pneumonia. Female sex (OR 2.55, 95% CI 1.30-5.04), severe sepsis or septic shock (OR 3.05, 95% CI 1.09-8.55), prior hospitalization within the previous year (OR 2.18, 95% CI 1.10-4.32) and surgical site infection (SSI) (OR 4.63, 95% CI 1.38-15.59) were associated with ST72-MRSA-IV infections in multivariate analyses.

CONCLUSIONS

Female sex, SSI, severe sepsis or septic shock and prior hospitalization within the previous year were predictors of ST72-MRSA-IV among patients with CO S. aureus infection.

Authors+Show Affiliations

Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22514264

Citation

Joo, Eun-Jeong, et al. "Clinical Predictors of Community-genotype ST72-methicillin-resistant Staphylococcus aureus-SCCmec Type IV in Patients With Community-onset S. Aureus Infection." The Journal of Antimicrobial Chemotherapy, vol. 67, no. 7, 2012, pp. 1755-9.
Joo EJ, Chung DR, Ha YE, et al. Clinical predictors of community-genotype ST72-methicillin-resistant Staphylococcus aureus-SCCmec type IV in patients with community-onset S. aureus infection. J Antimicrob Chemother. 2012;67(7):1755-9.
Joo, E. J., Chung, D. R., Ha, Y. E., Park, S. Y., Kim, H. A., Lim, M. H., ... Song, J. H. (2012). Clinical predictors of community-genotype ST72-methicillin-resistant Staphylococcus aureus-SCCmec type IV in patients with community-onset S. aureus infection. The Journal of Antimicrobial Chemotherapy, 67(7), pp. 1755-9. doi:10.1093/jac/dks120.
Joo EJ, et al. Clinical Predictors of Community-genotype ST72-methicillin-resistant Staphylococcus aureus-SCCmec Type IV in Patients With Community-onset S. Aureus Infection. J Antimicrob Chemother. 2012;67(7):1755-9. PubMed PMID: 22514264.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical predictors of community-genotype ST72-methicillin-resistant Staphylococcus aureus-SCCmec type IV in patients with community-onset S. aureus infection. AU - Joo,Eun-Jeong, AU - Chung,Doo Ryeon, AU - Ha,Young Eun, AU - Park,So Yeon, AU - Kim,Hyun Ah, AU - Lim,Min Hee, AU - Kim,So Hyun, AU - Kang,Cheol-In, AU - Lee,Nam Yong, AU - Ko,Kwan Soo, AU - Peck,Kyong Ran, AU - Song,Jae-Hoon, Y1 - 2012/04/18/ PY - 2012/4/20/entrez PY - 2012/4/20/pubmed PY - 2012/10/4/medline SP - 1755 EP - 9 JF - The Journal of antimicrobial chemotherapy JO - J. Antimicrob. Chemother. VL - 67 IS - 7 N2 - OBJECTIVES: Community-genotype methicillin-resistant Staphylococcus aureus (MRSA) clones have emerged in the community worldwide and recently have been spreading into the hospitals. To identify predictors of sequence type 72-MRSA-SCCmec type IV (ST72-MRSA-IV) in patients with community-onset (CO) S. aureus infection, a case-control study was conducted among CO S. aureus infections, including healthcare-associated infections. METHODS: Eighty-four patients with CO infections caused by ST72-MRSA-IV strains in Korea between 2007 and 2009 were selected as cases. Members of the control group were those with CO methicillin-susceptible S. aureus infections and they were matched by the admission date in a 1 : 1 ratio. RESULTS: The most common type of infection was skin and soft tissue infection in both groups (48.8% versus 52.4%), followed by pneumonia. Female sex (OR 2.55, 95% CI 1.30-5.04), severe sepsis or septic shock (OR 3.05, 95% CI 1.09-8.55), prior hospitalization within the previous year (OR 2.18, 95% CI 1.10-4.32) and surgical site infection (SSI) (OR 4.63, 95% CI 1.38-15.59) were associated with ST72-MRSA-IV infections in multivariate analyses. CONCLUSIONS: Female sex, SSI, severe sepsis or septic shock and prior hospitalization within the previous year were predictors of ST72-MRSA-IV among patients with CO S. aureus infection. SN - 1460-2091 UR - https://www.unboundmedicine.com/medline/citation/22514264/Clinical_predictors_of_community_genotype_ST72_methicillin_resistant_Staphylococcus_aureus_SCCmec_type_IV_in_patients_with_community_onset_S__aureus_infection_ L2 - https://academic.oup.com/jac/article-lookup/doi/10.1093/jac/dks120 DB - PRIME DP - Unbound Medicine ER -