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Aspirin-exacerbated respiratory disease: burden of disease.
Allergy Asthma Proc. 2012 Mar-Apr; 33(2):117-21.AA

Abstract

Aspirin-exacerbated respiratory disease (AERD) is characterized by adult onset of asthma, chronic rhinosinusitis (CRS), nasal polyposis, and aspirin sensitivity. In this syndrome, each disease component has deleterious effects on the patient's health and quality of life. Latest figures from the Centers for Disease Control indicate 8.2% of the U.S. population has asthma and among adult asthmatic patients, up to 9% have AERD. Approximately 13% of the population suffers from CRS and 15% of patients with CRS with nasal polyposis have AERD. A review of the impact that each component of AERD has on patients will delineate the considerable burden of AERD, especially when considering the cumulative effects of the tetrad.

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Publisher Full Text

Authors+Show Affiliations

Chang JE
Scripps Clinic, La Jolla, California, USA. Chang.Jinny@scrippshealth.org
White A
No affiliation info available
Simon RA
No affiliation info available
Stevenson DD
No affiliation info available

MeSH

Anti-Inflammatory Agents, Non-SteroidalAspirinAsthma, Aspirin-InducedChronic DiseaseCost of IllnessCyclooxygenase InhibitorsHumansNasal PolypsOlfaction DisordersQuality of LifeRespiratory Tract DiseasesRhinitisSinusitisUnited States

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22525387

Clinical Trial Links

The Effect of Aspirin Desensitization on Patients With Aspirin-exacerbated Respiratory Diseases

Citation

Chang, Jinny E., et al. "Aspirin-exacerbated Respiratory Disease: Burden of Disease." Allergy and Asthma Proceedings, vol. 33, no. 2, 2012, pp. 117-21.
Chang JE, White A, Simon RA, et al. Aspirin-exacerbated respiratory disease: burden of disease. Allergy Asthma Proc. 2012;33(2):117-21.
Chang, J. E., White, A., Simon, R. A., & Stevenson, D. D. (2012). Aspirin-exacerbated respiratory disease: burden of disease. Allergy and Asthma Proceedings, 33(2), 117-21. https://doi.org/10.2500/aap.2012.33.3541
Chang JE, et al. Aspirin-exacerbated Respiratory Disease: Burden of Disease. Allergy Asthma Proc. 2012 Mar-Apr;33(2):117-21. PubMed PMID: 22525387.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Aspirin-exacerbated respiratory disease: burden of disease. AU - Chang,Jinny E, AU - White,Andrew, AU - Simon,Ronald A, AU - Stevenson,Donald D, PY - 2012/4/25/entrez PY - 2012/4/25/pubmed PY - 2012/8/15/medline SP - 117 EP - 21 JF - Allergy and asthma proceedings JO - Allergy Asthma Proc VL - 33 IS - 2 N2 - Aspirin-exacerbated respiratory disease (AERD) is characterized by adult onset of asthma, chronic rhinosinusitis (CRS), nasal polyposis, and aspirin sensitivity. In this syndrome, each disease component has deleterious effects on the patient's health and quality of life. Latest figures from the Centers for Disease Control indicate 8.2% of the U.S. population has asthma and among adult asthmatic patients, up to 9% have AERD. Approximately 13% of the population suffers from CRS and 15% of patients with CRS with nasal polyposis have AERD. A review of the impact that each component of AERD has on patients will delineate the considerable burden of AERD, especially when considering the cumulative effects of the tetrad. SN - 1539-6304 UR - https://www.unboundmedicine.com/medline/citation/22525387/Aspirin_exacerbated_respiratory_disease:_burden_of_disease_ L2 - https://www.ingentaconnect.com/openurl?genre=article&issn=1088-5412&volume=33&issue=2&spage=117&aulast=Chang DB - PRIME DP - Unbound Medicine ER -