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A comparative assessment of survival between propensity score-matched patients with peritoneal dialysis and hemodialysis in Taiwan.
Medicine (Baltimore). 2012 May; 91(3):144-151.M

Abstract

Studies comparing mortality for Asian populations with end-stage renal disease (ESRD) on hemodialysis (HD) and peritoneal dialysis (PD) are limited. We compared mortality between patients treated with PD and HD in Taiwan, the population with the highest incidence of ESRD worldwide. Using the population-based insurance claims data of Taiwan from 1997 to 2006, we identified 4721 patients treated with PD and randomly selected 4721 patients treated with HD who were frequency-matched to the PD patients based on their propensity scores. In follow-up analyses we measured mortalities and hazard ratios associated with comorbidities in 2 different 5-year cohorts (1997-2001 and 2002-2006).In the 10-year period from 1997 to 2006, the overall mortality rates were similar in patients treated with PD and in patients treated with HD (12.0 vs. 11.7 per 100 person-years, respectively), with a PD-to-HD hazard ratio of 1.02 (95% confidence interval [CI], 0.96-1.08). In the first 5-year period (1997-2001), the hazard ratio for mortality was higher for PD (1.33; 95% CI, 1.21-1.46), but there was no difference between PD and HD in the 2002-2006 cohort. Of note, younger patients who received PD had better survival than younger patients who received HD; this was especially true for patients aged younger than 40 years.In summary, in this Asian population, no significant survival differences were noted between propensity score-matched PD and HD patients. The selection of a dialysis modality must be tailored to the individual patient. Studies in which patients who are appropriate for either modality are randomly assigned to HD or PD may provide helpful information to clinicians and patients.

Authors+Show Affiliations

From the Institute of Population Health Sciences (YKC, CC Hsu), National Health Research Institutes, Zhunan, Taiwan; Department of Public Health (YKC, PCC, FCS), Division of Nephrology (CC Huang), and Institute of Biostatistics (TCL), China Medical University and Hospital, Taichung, Taiwan; and Division of Nephrology (SJH), Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22525667

Citation

Chang, Yu-Kang, et al. "A Comparative Assessment of Survival Between Propensity Score-matched Patients With Peritoneal Dialysis and Hemodialysis in Taiwan." Medicine, vol. 91, no. 3, 2012, pp. 144-151.
Chang YK, Hsu CC, Hwang SJ, et al. A comparative assessment of survival between propensity score-matched patients with peritoneal dialysis and hemodialysis in Taiwan. Medicine (Baltimore). 2012;91(3):144-151.
Chang, Y. K., Hsu, C. C., Hwang, S. J., Chen, P. C., Huang, C. C., Li, T. C., & Sung, F. C. (2012). A comparative assessment of survival between propensity score-matched patients with peritoneal dialysis and hemodialysis in Taiwan. Medicine, 91(3), 144-151. https://doi.org/10.1097/MD.0b013e318256538e
Chang YK, et al. A Comparative Assessment of Survival Between Propensity Score-matched Patients With Peritoneal Dialysis and Hemodialysis in Taiwan. Medicine (Baltimore). 2012;91(3):144-151. PubMed PMID: 22525667.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A comparative assessment of survival between propensity score-matched patients with peritoneal dialysis and hemodialysis in Taiwan. AU - Chang,Yu-Kang, AU - Hsu,Chih-Cheng, AU - Hwang,Shang-Jyh, AU - Chen,Pei-Chun, AU - Huang,Chiu-Chin, AU - Li,Tsai-Chung, AU - Sung,Fung-Chang, PY - 2012/4/25/entrez PY - 2012/4/25/pubmed PY - 2012/7/26/medline SP - 144 EP - 151 JF - Medicine JO - Medicine (Baltimore) VL - 91 IS - 3 N2 - Studies comparing mortality for Asian populations with end-stage renal disease (ESRD) on hemodialysis (HD) and peritoneal dialysis (PD) are limited. We compared mortality between patients treated with PD and HD in Taiwan, the population with the highest incidence of ESRD worldwide. Using the population-based insurance claims data of Taiwan from 1997 to 2006, we identified 4721 patients treated with PD and randomly selected 4721 patients treated with HD who were frequency-matched to the PD patients based on their propensity scores. In follow-up analyses we measured mortalities and hazard ratios associated with comorbidities in 2 different 5-year cohorts (1997-2001 and 2002-2006).In the 10-year period from 1997 to 2006, the overall mortality rates were similar in patients treated with PD and in patients treated with HD (12.0 vs. 11.7 per 100 person-years, respectively), with a PD-to-HD hazard ratio of 1.02 (95% confidence interval [CI], 0.96-1.08). In the first 5-year period (1997-2001), the hazard ratio for mortality was higher for PD (1.33; 95% CI, 1.21-1.46), but there was no difference between PD and HD in the 2002-2006 cohort. Of note, younger patients who received PD had better survival than younger patients who received HD; this was especially true for patients aged younger than 40 years.In summary, in this Asian population, no significant survival differences were noted between propensity score-matched PD and HD patients. The selection of a dialysis modality must be tailored to the individual patient. Studies in which patients who are appropriate for either modality are randomly assigned to HD or PD may provide helpful information to clinicians and patients. SN - 1536-5964 UR - https://www.unboundmedicine.com/medline/citation/22525667/A_comparative_assessment_of_survival_between_propensity_score_matched_patients_with_peritoneal_dialysis_and_hemodialysis_in_Taiwan_ L2 - https://doi.org/10.1097/MD.0b013e318256538e DB - PRIME DP - Unbound Medicine ER -