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Endometrial abnormality in women with polycystic ovary syndrome.
Reprod Sci. 2012 Jul; 19(7):674-83.RS

Abstract

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy associated with infertility and metabolic disorder in women of reproductive age. Although the clinical and biochemical features are heterogeneous with individuals, the most widely accepted clinical characteristics of PCOS are oligo- or anovulation combined with hyperandrogenism. With the higher rate of implantation failure after induction of ovulation or higher risk of spontaneous miscarriage after pregnancy, the reduced fertility is apparently attributed not only to anovulation but also to endometrial dysfunction in patients with PCOS. Here we review the features of the endometrial abnormalities in women with PCOS. The ability to improve the endometrial functions is of potential therapeutic targets to increase reproductive outcome of women with PCOS.

Authors+Show Affiliations

Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

22534323

Citation

Shang, Kewei, et al. "Endometrial Abnormality in Women With Polycystic Ovary Syndrome." Reproductive Sciences (Thousand Oaks, Calif.), vol. 19, no. 7, 2012, pp. 674-83.
Shang K, Jia X, Qiao J, et al. Endometrial abnormality in women with polycystic ovary syndrome. Reprod Sci. 2012;19(7):674-83.
Shang, K., Jia, X., Qiao, J., Kang, J., & Guan, Y. (2012). Endometrial abnormality in women with polycystic ovary syndrome. Reproductive Sciences (Thousand Oaks, Calif.), 19(7), 674-83. https://doi.org/10.1177/1933719111430993
Shang K, et al. Endometrial Abnormality in Women With Polycystic Ovary Syndrome. Reprod Sci. 2012;19(7):674-83. PubMed PMID: 22534323.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endometrial abnormality in women with polycystic ovary syndrome. AU - Shang,Kewei, AU - Jia,Xiao, AU - Qiao,Jie, AU - Kang,Jihong, AU - Guan,Youfei, Y1 - 2012/04/24/ PY - 2012/4/27/entrez PY - 2012/4/27/pubmed PY - 2012/12/10/medline SP - 674 EP - 83 JF - Reproductive sciences (Thousand Oaks, Calif.) JO - Reprod Sci VL - 19 IS - 7 N2 - Polycystic ovary syndrome (PCOS) is the most common endocrinopathy associated with infertility and metabolic disorder in women of reproductive age. Although the clinical and biochemical features are heterogeneous with individuals, the most widely accepted clinical characteristics of PCOS are oligo- or anovulation combined with hyperandrogenism. With the higher rate of implantation failure after induction of ovulation or higher risk of spontaneous miscarriage after pregnancy, the reduced fertility is apparently attributed not only to anovulation but also to endometrial dysfunction in patients with PCOS. Here we review the features of the endometrial abnormalities in women with PCOS. The ability to improve the endometrial functions is of potential therapeutic targets to increase reproductive outcome of women with PCOS. SN - 1933-7205 UR - https://www.unboundmedicine.com/medline/citation/22534323/Endometrial_abnormality_in_women_with_polycystic_ovary_syndrome_ L2 - http://journals.sagepub.com/doi/full/10.1177/1933719111430993?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -