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[Hepatitis E. Current perspectives].
Med Clin (Barc). 2012 Oct 13; 139(9):404-11.MC

Abstract

Infection with hepatitis E virus (HEV) is highly prevalent in developing countries and the WHO estimates one third of the world population has had contact with the virus. Its diagnosis and epidemiology are well known in endemic countries but, recently, there have been sporadic cases in developed countries in patients with no history of travel. Currently in these countries, hepatitis E is considered a zoonosis yet there remain to be known other routes of transmission. Another interesting aspect is that HEV can cause chronic hepatitis in transplanted patients, other immunocompromised patients and even in immunocompetent people. There have also been reported cases of fulminant hepatitis and other extrahepatic manifestations. The diagnosis is based on serological studies and detection of viral RNA in blood and feces. The vaccine is a good option to prevent this infection that affects a large number of people in deprived geographical areas but unfortunately it is not available yet.

Authors+Show Affiliations

Departamento de Microbiología, Facultad de Ciencias de la Salud, Universidad CEU Cardenal Herrera, Moncada, Valencia, Spain. teresa@uch.ceu.esNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

spa

PubMed ID

22538059

Citation

Pérez-Gracia, María Teresa, and María Luisa Mateos-Lindemann. "[Hepatitis E. Current Perspectives]." Medicina Clinica, vol. 139, no. 9, 2012, pp. 404-11.
Pérez-Gracia MT, Mateos-Lindemann ML. [Hepatitis E. Current perspectives]. Med Clin (Barc). 2012;139(9):404-11.
Pérez-Gracia, M. T., & Mateos-Lindemann, M. L. (2012). [Hepatitis E. Current perspectives]. Medicina Clinica, 139(9), 404-11. https://doi.org/10.1016/j.medcli.2012.02.013
Pérez-Gracia MT, Mateos-Lindemann ML. [Hepatitis E. Current Perspectives]. Med Clin (Barc). 2012 Oct 13;139(9):404-11. PubMed PMID: 22538059.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Hepatitis E. Current perspectives]. AU - Pérez-Gracia,María Teresa, AU - Mateos-Lindemann,María Luisa, Y1 - 2012/04/24/ PY - 2011/12/31/received PY - 2012/02/14/revised PY - 2012/02/23/accepted PY - 2012/4/28/entrez PY - 2012/4/28/pubmed PY - 2013/3/5/medline SP - 404 EP - 11 JF - Medicina clinica JO - Med Clin (Barc) VL - 139 IS - 9 N2 - Infection with hepatitis E virus (HEV) is highly prevalent in developing countries and the WHO estimates one third of the world population has had contact with the virus. Its diagnosis and epidemiology are well known in endemic countries but, recently, there have been sporadic cases in developed countries in patients with no history of travel. Currently in these countries, hepatitis E is considered a zoonosis yet there remain to be known other routes of transmission. Another interesting aspect is that HEV can cause chronic hepatitis in transplanted patients, other immunocompromised patients and even in immunocompetent people. There have also been reported cases of fulminant hepatitis and other extrahepatic manifestations. The diagnosis is based on serological studies and detection of viral RNA in blood and feces. The vaccine is a good option to prevent this infection that affects a large number of people in deprived geographical areas but unfortunately it is not available yet. SN - 1578-8989 UR - https://www.unboundmedicine.com/medline/citation/22538059/[Hepatitis_E__Current_perspectives]_ L2 - http://www.elsevier.es/en/linksolver/ft/pii/S0025-7753(12)00221-7 DB - PRIME DP - Unbound Medicine ER -