Tags

Type your tag names separated by a space and hit enter

Association of sweetened beverage intake with incident hypertension.
J Gen Intern Med 2012; 27(9):1127-34JG

Abstract

BACKGROUND

Consumption of sugar-sweetened beverages (SSBs) is associated with an increased risk of hypertension in cross-sectional studies. However, prospective data are limited.

OBJECTIVE

To examine the associations between SSBs and artificially sweetened beverages (ASBs) with incident hypertension.

DESIGN AND SETTING

Prospective analysis using Cox proportional hazards regression to examine the association between SSBs and ASBs with incident hypertension in three large, prospective cohorts, the Nurses' Health Studies I (n = 88,540 women) and II (n = 97,991 women) and the Health Professionals' Follow-Up Study (n = 37,360 men).

MEASUREMENTS

Adjusted hazard ratios for incident clinically diagnosed hypertension.

RESULTS

Higher SSB and ASB intake was associated with an increased risk of developing hypertension in all three cohorts. In a pooled analysis, participants who consumed at least one SSB daily had an adjusted HR for incident hypertension of 1.13 (95 % CI, 1.09-1.17) compared with those who did not consume SSBs; for persons who drank at least one ASB daily, the adjusted HR was 1.14 (95 % CI, 1.09-1.18). The association between sweetened beverage intake and hypertension was stronger for carbonated beverages versus non-carbonated beverages, and for cola-containing versus non-cola beverages in the NHS I and NHS II cohorts only. Higher fructose intake from SSBs as a percentage of daily calories was associated with increased hypertension risk in NHS I and NHS II (p-trend = 0.001 in both groups), while higher fructose intake from sources other than SSBs was associated with a decrease in hypertension risk in NHS II participants (p-trend = 0.006).

LIMITATIONS

Residual confounding factors may interfere with the interpretation of results.

CONCLUSIONS

SSBs and ASBs are independently associated with an increased risk of incident hypertension after controlling for multiple potential confounders. These associations may be mediated by factors common to both SSBs and ASBs (e.g., carbonation or cola), but are unlikely to be due to fructose.

Authors+Show Affiliations

Division of Nephrology, University of Maryland Medical Center, Baltimore, MD, USA. lcohen@medicine.umaryland.eduNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22539069

Citation

Cohen, Lisa, et al. "Association of Sweetened Beverage Intake With Incident Hypertension." Journal of General Internal Medicine, vol. 27, no. 9, 2012, pp. 1127-34.
Cohen L, Curhan G, Forman J. Association of sweetened beverage intake with incident hypertension. J Gen Intern Med. 2012;27(9):1127-34.
Cohen, L., Curhan, G., & Forman, J. (2012). Association of sweetened beverage intake with incident hypertension. Journal of General Internal Medicine, 27(9), pp. 1127-34. doi:10.1007/s11606-012-2069-6.
Cohen L, Curhan G, Forman J. Association of Sweetened Beverage Intake With Incident Hypertension. J Gen Intern Med. 2012;27(9):1127-34. PubMed PMID: 22539069.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association of sweetened beverage intake with incident hypertension. AU - Cohen,Lisa, AU - Curhan,Gary, AU - Forman,John, Y1 - 2012/04/27/ PY - 2011/11/08/received PY - 2012/03/30/accepted PY - 2012/01/30/revised PY - 2012/4/28/entrez PY - 2012/4/28/pubmed PY - 2013/6/12/medline SP - 1127 EP - 34 JF - Journal of general internal medicine JO - J Gen Intern Med VL - 27 IS - 9 N2 - BACKGROUND: Consumption of sugar-sweetened beverages (SSBs) is associated with an increased risk of hypertension in cross-sectional studies. However, prospective data are limited. OBJECTIVE: To examine the associations between SSBs and artificially sweetened beverages (ASBs) with incident hypertension. DESIGN AND SETTING: Prospective analysis using Cox proportional hazards regression to examine the association between SSBs and ASBs with incident hypertension in three large, prospective cohorts, the Nurses' Health Studies I (n = 88,540 women) and II (n = 97,991 women) and the Health Professionals' Follow-Up Study (n = 37,360 men). MEASUREMENTS: Adjusted hazard ratios for incident clinically diagnosed hypertension. RESULTS: Higher SSB and ASB intake was associated with an increased risk of developing hypertension in all three cohorts. In a pooled analysis, participants who consumed at least one SSB daily had an adjusted HR for incident hypertension of 1.13 (95 % CI, 1.09-1.17) compared with those who did not consume SSBs; for persons who drank at least one ASB daily, the adjusted HR was 1.14 (95 % CI, 1.09-1.18). The association between sweetened beverage intake and hypertension was stronger for carbonated beverages versus non-carbonated beverages, and for cola-containing versus non-cola beverages in the NHS I and NHS II cohorts only. Higher fructose intake from SSBs as a percentage of daily calories was associated with increased hypertension risk in NHS I and NHS II (p-trend = 0.001 in both groups), while higher fructose intake from sources other than SSBs was associated with a decrease in hypertension risk in NHS II participants (p-trend = 0.006). LIMITATIONS: Residual confounding factors may interfere with the interpretation of results. CONCLUSIONS: SSBs and ASBs are independently associated with an increased risk of incident hypertension after controlling for multiple potential confounders. These associations may be mediated by factors common to both SSBs and ASBs (e.g., carbonation or cola), but are unlikely to be due to fructose. SN - 1525-1497 UR - https://www.unboundmedicine.com/medline/citation/22539069/Association_of_sweetened_beverage_intake_with_incident_hypertension_ L2 - https://dx.doi.org/10.1007/s11606-012-2069-6 DB - PRIME DP - Unbound Medicine ER -