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Production and in vitro antioxidant activity of exopolysaccharide by a mutant, Cordyceps militaris SU5-08.
Int J Biol Macromol. 2012 Jul-Aug; 51(1-2):153-7.IJ

Abstract

Cordyceps militaris SU5-08 was derived from an initial strain (C. militaris SU5) by ultraviolet mutagenesis of protoplasts, and the extraction parameters for C. militaris SU5-08 exopolysaccharide (EPS) produced during submerged culture were optimized. The extraction rate of EPS was 1919.16±165.27 mg/l, which was 120.38±11.36% higher than that of C. militaris SU5. The in vitro scavenging effects of EPS of C. militaris SU5-08 on hydroxyl, superoxide anion and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals at a dosage of 5 g/l were 63.64±3.52%, 75.27±5.16%, and 6.46±5.03%, respectively. The reducing power of EPS of C. militaris SU5-08 was 0.21±0.01. The results suggest that the EPS of C. militaris SU5-08 can be used as a potential antioxidant which enhances adaptive immune responses.

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Authors+Show Affiliations

Lin R
College of Life Science, Shandong Agricultural University, Taian, Shandong 271018, PR China.
Liu H
No affiliation info available
Wu S
No affiliation info available
Pang L
No affiliation info available
Jia M
No affiliation info available
Fan K
No affiliation info available
Jia S
No affiliation info available
Jia L
No affiliation info available

MeSH

AntioxidantsCordycepsHydroxyl RadicalMutationOxidation-ReductionPolysaccharidesSuperoxides

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22542852

Citation

Lin, Rongshan, et al. "Production and in Vitro Antioxidant Activity of Exopolysaccharide By a Mutant, Cordyceps Militaris SU5-08." International Journal of Biological Macromolecules, vol. 51, no. 1-2, 2012, pp. 153-7.
Lin R, Liu H, Wu S, et al. Production and in vitro antioxidant activity of exopolysaccharide by a mutant, Cordyceps militaris SU5-08. Int J Biol Macromol. 2012;51(1-2):153-7.
Lin, R., Liu, H., Wu, S., Pang, L., Jia, M., Fan, K., Jia, S., & Jia, L. (2012). Production and in vitro antioxidant activity of exopolysaccharide by a mutant, Cordyceps militaris SU5-08. International Journal of Biological Macromolecules, 51(1-2), 153-7. https://doi.org/10.1016/j.ijbiomac.2012.04.011
Lin R, et al. Production and in Vitro Antioxidant Activity of Exopolysaccharide By a Mutant, Cordyceps Militaris SU5-08. Int J Biol Macromol. 2012 Jul-Aug;51(1-2):153-7. PubMed PMID: 22542852.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Production and in vitro antioxidant activity of exopolysaccharide by a mutant, Cordyceps militaris SU5-08. AU - Lin,Rongshan, AU - Liu,Honghong, AU - Wu,Suqian, AU - Pang,Lifei, AU - Jia,Mengshi, AU - Fan,Keming, AU - Jia,Shouhua, AU - Jia,Le, Y1 - 2012/04/20/ PY - 2012/02/23/received PY - 2012/03/30/revised PY - 2012/04/13/accepted PY - 2012/5/1/entrez PY - 2012/5/1/pubmed PY - 2012/10/20/medline SP - 153 EP - 7 JF - International journal of biological macromolecules JO - Int J Biol Macromol VL - 51 IS - 1-2 N2 - Cordyceps militaris SU5-08 was derived from an initial strain (C. militaris SU5) by ultraviolet mutagenesis of protoplasts, and the extraction parameters for C. militaris SU5-08 exopolysaccharide (EPS) produced during submerged culture were optimized. The extraction rate of EPS was 1919.16±165.27 mg/l, which was 120.38±11.36% higher than that of C. militaris SU5. The in vitro scavenging effects of EPS of C. militaris SU5-08 on hydroxyl, superoxide anion and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals at a dosage of 5 g/l were 63.64±3.52%, 75.27±5.16%, and 6.46±5.03%, respectively. The reducing power of EPS of C. militaris SU5-08 was 0.21±0.01. The results suggest that the EPS of C. militaris SU5-08 can be used as a potential antioxidant which enhances adaptive immune responses. SN - 1879-0003 UR - https://www.unboundmedicine.com/medline/citation/22542852/Production_and_in_vitro_antioxidant_activity_of_exopolysaccharide_by_a_mutant_Cordyceps_militaris_SU5_08_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0141-8130(12)00142-0 DB - PRIME DP - Unbound Medicine ER -