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Accumulation of sunscreen in human skin after daily applications: a study of sunscreens with different ultraviolet radiation filters.
Photodermatol Photoimmunol Photomed. 2012 Jun; 28(3):127-32.PP

Abstract

BACKGROUND/PURPOSE

Sunscreen applied to the skin provides a considerable sun protection factor (SPF) even after 8 h. Sunscreen use for consecutive days may therefore result in an accumulation of the product. This study investigated the consequences of accumulation for SPF.

METHODS

Two sunscreens, one containing organic and one containing particle ultraviolet radiation (UVR) filters (SPF 30) (2 mg/cm(2)), were used. Areas on the back of 22 volunteers were applied with sunscreen on 5 consecutive days, once daily (12 volunteers) and three times daily (10 volunteers), and phototested. The SPF was determined on Days 1, 3 and 5.

RESULTS

One daily application of sunscreen did not result in an accumulation in the skin that significantly affected the SPF. However, three daily applications provided a significantly higher SPF for both the organic (mean SPF 1.56) and particle (mean SPF 2.45) sunscreen at Day 5 compared to Day 1 (P = 0.023 for both sunscreens).

CONCLUSION

Sunscreens accumulate in the skin when applied in the recommended amounts three times daily. In conjunction with other sun protection strategies, sunscreen application on consecutive days prior to UVR exposure can result in a basic skin protection, which may help to prevent severe sunburns on sun holidays.

Authors+Show Affiliations

Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark. mettebodek@hotmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22548393

Citation

Bodekær, Mette, et al. "Accumulation of Sunscreen in Human Skin After Daily Applications: a Study of Sunscreens With Different Ultraviolet Radiation Filters." Photodermatology, Photoimmunology & Photomedicine, vol. 28, no. 3, 2012, pp. 127-32.
Bodekær M, Akerström U, Wulf HC. Accumulation of sunscreen in human skin after daily applications: a study of sunscreens with different ultraviolet radiation filters. Photodermatol Photoimmunol Photomed. 2012;28(3):127-32.
Bodekær, M., Akerström, U., & Wulf, H. C. (2012). Accumulation of sunscreen in human skin after daily applications: a study of sunscreens with different ultraviolet radiation filters. Photodermatology, Photoimmunology & Photomedicine, 28(3), 127-32. https://doi.org/10.1111/j.1600-0781.2012.00651.x
Bodekær M, Akerström U, Wulf HC. Accumulation of Sunscreen in Human Skin After Daily Applications: a Study of Sunscreens With Different Ultraviolet Radiation Filters. Photodermatol Photoimmunol Photomed. 2012;28(3):127-32. PubMed PMID: 22548393.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Accumulation of sunscreen in human skin after daily applications: a study of sunscreens with different ultraviolet radiation filters. AU - Bodekær,Mette, AU - Akerström,Ulf, AU - Wulf,Hans Christian, PY - 2012/5/3/entrez PY - 2012/5/3/pubmed PY - 2012/9/5/medline SP - 127 EP - 32 JF - Photodermatology, photoimmunology & photomedicine JO - Photodermatol Photoimmunol Photomed VL - 28 IS - 3 N2 - BACKGROUND/PURPOSE: Sunscreen applied to the skin provides a considerable sun protection factor (SPF) even after 8 h. Sunscreen use for consecutive days may therefore result in an accumulation of the product. This study investigated the consequences of accumulation for SPF. METHODS: Two sunscreens, one containing organic and one containing particle ultraviolet radiation (UVR) filters (SPF 30) (2 mg/cm(2)), were used. Areas on the back of 22 volunteers were applied with sunscreen on 5 consecutive days, once daily (12 volunteers) and three times daily (10 volunteers), and phototested. The SPF was determined on Days 1, 3 and 5. RESULTS: One daily application of sunscreen did not result in an accumulation in the skin that significantly affected the SPF. However, three daily applications provided a significantly higher SPF for both the organic (mean SPF 1.56) and particle (mean SPF 2.45) sunscreen at Day 5 compared to Day 1 (P = 0.023 for both sunscreens). CONCLUSION: Sunscreens accumulate in the skin when applied in the recommended amounts three times daily. In conjunction with other sun protection strategies, sunscreen application on consecutive days prior to UVR exposure can result in a basic skin protection, which may help to prevent severe sunburns on sun holidays. SN - 1600-0781 UR - https://www.unboundmedicine.com/medline/citation/22548393/Accumulation_of_sunscreen_in_human_skin_after_daily_applications:_a_study_of_sunscreens_with_different_ultraviolet_radiation_filters_ DB - PRIME DP - Unbound Medicine ER -