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[Fear memory extinction accelerated by simultaneous activation of GABA(B) and NMDA receptors].
Eksp Klin Farmakol. 2012; 75(2):7-9.EK

Abstract

Effects of the N-methyl-D-aspartate (NMDA) agonist (D-cycloserine) and GABA(B) agonist (baclofen) on the fear memory extinction as manifested in the passive avoidance reaction in C57Bl/6J mice with "behavioral despair" (model of depression) and without previously developed stress have been studied. The positive acceleration of the fear memory extinction was observed in depressive mice upon the simultaneous administration of D-cycloserine and baclofen.

Authors

Dubrovina NI
No affiliation info available

MeSH

AnimalsAntimetabolitesAvoidance LearningBaclofenCycloserineDepressionExtinction, PsychologicalFearGABA-B Receptor AgonistsMaleMemoryMiceMice, Inbred C57BLReceptors, GABA-BReceptors, N-Methyl-D-Aspartate

Pub Type(s)

English Abstract
Journal Article

Language

rus

PubMed ID

22550851

Citation

Dubrovina, N I.. "[Fear Memory Extinction Accelerated By Simultaneous Activation of GABA(B) and NMDA Receptors]." Eksperimental'naia I Klinicheskaia Farmakologiia, vol. 75, no. 2, 2012, pp. 7-9.
Dubrovina NI. [Fear memory extinction accelerated by simultaneous activation of GABA(B) and NMDA receptors]. Eksp Klin Farmakol. 2012;75(2):7-9.
Dubrovina, N. I. (2012). [Fear memory extinction accelerated by simultaneous activation of GABA(B) and NMDA receptors]. Eksperimental'naia I Klinicheskaia Farmakologiia, 75(2), 7-9.
Dubrovina NI. [Fear Memory Extinction Accelerated By Simultaneous Activation of GABA(B) and NMDA Receptors]. Eksp Klin Farmakol. 2012;75(2):7-9. PubMed PMID: 22550851.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Fear memory extinction accelerated by simultaneous activation of GABA(B) and NMDA receptors]. A1 - Dubrovina,N I, PY - 2012/5/4/entrez PY - 2012/5/4/pubmed PY - 2012/5/30/medline SP - 7 EP - 9 JF - Eksperimental'naia i klinicheskaia farmakologiia JO - Eksp Klin Farmakol VL - 75 IS - 2 N2 - Effects of the N-methyl-D-aspartate (NMDA) agonist (D-cycloserine) and GABA(B) agonist (baclofen) on the fear memory extinction as manifested in the passive avoidance reaction in C57Bl/6J mice with "behavioral despair" (model of depression) and without previously developed stress have been studied. The positive acceleration of the fear memory extinction was observed in depressive mice upon the simultaneous administration of D-cycloserine and baclofen. SN - 0869-2092 UR - https://www.unboundmedicine.com/medline/citation/22550851/[Fear_memory_extinction_accelerated_by_simultaneous_activation_of_GABA_B__and_NMDA_receptors]_ L2 - https://medlineplus.gov/depression.html DB - PRIME DP - Unbound Medicine ER -