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Plain-water intake and risk of type 2 diabetes in young and middle-aged women.
Am J Clin Nutr. 2012 Jun; 95(6):1454-60.AJ

Abstract

BACKGROUND

The replacement of caloric beverages such as sugar-sweetened beverages (SSBs) and fruit juices with noncaloric beverages such as plain water has been recommended for diabetes prevention.

OBJECTIVE

We evaluated the relation of plain-water intake and the substitution of plain water for SSBs and fruit juices with incident type 2 diabetes (T2D) in US women.

DESIGN

We prospectively followed 82,902 women in the Nurses' Health Study II who were free of diabetes, cardiovascular disease, or cancer at baseline. Diet, including various beverages, was assessed by using validated food-frequency questionnaires and updated every 4 y. Incident T2D was confirmed by using a validated supplementary questionnaire. We used a 4-y lagged analysis to minimize reverse causation (ie, increased water consumption that was due to early stage of diabetes).

RESULTS

During 1,115,427 person-years of follow-up, we documented 2718 incident T2D cases. Plain-water intake was not associated with T2D risk in the multivariable-adjusted model that included age, BMI, diet, and lifestyle factors; RRs (95% CIs) across categories (<1, 1, 2-3, 4-5, and ≥6 cups/d) were 1.00, 0.93 (0.82, 1.05), 0.93 (0.83, 1.05), 1.09 (0.96, 1.24), and 1.06 (0.91, 1.23), respectively (P-trend = 0.15). We estimated that the replacement of 1 serving SSBs and fruit juices/d by 1 cup plain water/d was associated with 7% (3%, 11%) and 8% (2%, 13%) lower risk of T2D, respectively.

CONCLUSIONS

Plain-water intake, per se, was not significantly associated with risk of T2D. However, substitution of plain water for SSBs or fruit juices was estimated to be associated with modestly lower risk of T2D.

Authors+Show Affiliations

Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

22552035

Citation

Pan, An, et al. "Plain-water Intake and Risk of Type 2 Diabetes in Young and Middle-aged Women." The American Journal of Clinical Nutrition, vol. 95, no. 6, 2012, pp. 1454-60.
Pan A, Malik VS, Schulze MB, et al. Plain-water intake and risk of type 2 diabetes in young and middle-aged women. Am J Clin Nutr. 2012;95(6):1454-60.
Pan, A., Malik, V. S., Schulze, M. B., Manson, J. E., Willett, W. C., & Hu, F. B. (2012). Plain-water intake and risk of type 2 diabetes in young and middle-aged women. The American Journal of Clinical Nutrition, 95(6), 1454-60. https://doi.org/10.3945/ajcn.111.032698
Pan A, et al. Plain-water Intake and Risk of Type 2 Diabetes in Young and Middle-aged Women. Am J Clin Nutr. 2012;95(6):1454-60. PubMed PMID: 22552035.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Plain-water intake and risk of type 2 diabetes in young and middle-aged women. AU - Pan,An, AU - Malik,Vasanti S, AU - Schulze,Matthias B, AU - Manson,Joann E, AU - Willett,Walter C, AU - Hu,Frank B, Y1 - 2012/05/02/ PY - 2012/5/4/entrez PY - 2012/5/4/pubmed PY - 2012/7/28/medline SP - 1454 EP - 60 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 95 IS - 6 N2 - BACKGROUND: The replacement of caloric beverages such as sugar-sweetened beverages (SSBs) and fruit juices with noncaloric beverages such as plain water has been recommended for diabetes prevention. OBJECTIVE: We evaluated the relation of plain-water intake and the substitution of plain water for SSBs and fruit juices with incident type 2 diabetes (T2D) in US women. DESIGN: We prospectively followed 82,902 women in the Nurses' Health Study II who were free of diabetes, cardiovascular disease, or cancer at baseline. Diet, including various beverages, was assessed by using validated food-frequency questionnaires and updated every 4 y. Incident T2D was confirmed by using a validated supplementary questionnaire. We used a 4-y lagged analysis to minimize reverse causation (ie, increased water consumption that was due to early stage of diabetes). RESULTS: During 1,115,427 person-years of follow-up, we documented 2718 incident T2D cases. Plain-water intake was not associated with T2D risk in the multivariable-adjusted model that included age, BMI, diet, and lifestyle factors; RRs (95% CIs) across categories (<1, 1, 2-3, 4-5, and ≥6 cups/d) were 1.00, 0.93 (0.82, 1.05), 0.93 (0.83, 1.05), 1.09 (0.96, 1.24), and 1.06 (0.91, 1.23), respectively (P-trend = 0.15). We estimated that the replacement of 1 serving SSBs and fruit juices/d by 1 cup plain water/d was associated with 7% (3%, 11%) and 8% (2%, 13%) lower risk of T2D, respectively. CONCLUSIONS: Plain-water intake, per se, was not significantly associated with risk of T2D. However, substitution of plain water for SSBs or fruit juices was estimated to be associated with modestly lower risk of T2D. SN - 1938-3207 UR - https://www.unboundmedicine.com/medline/citation/22552035/Plain_water_intake_and_risk_of_type_2_diabetes_in_young_and_middle_aged_women_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.3945/ajcn.111.032698 DB - PRIME DP - Unbound Medicine ER -