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Treatment of refractory catatonic schizophrenia with low dose aripiprazole.
Ann Gen Psychiatry. 2012 May 03; 11(1):12.AG

Abstract

This case is of 54-year-old female with catatonic schizophrenia, characterized by treatment resistance to the pharmacotherapy with olanzapine, risperidone, flunitrazepam, and ECT. Olanzapine and risperidone and flunitrazepam did not improve her catatonic and psychotic symptoms, and induced the extrapyramidal symptoms. The effects of ECT did not continue even for a month. However, the treatment with low-dose aripiprazole dramatically improved the patient's psychotic symptoms and extrapyramidal symptoms. The mechanisms underlying the effects of low-dose aripiprazole in this case remain unclear, but unlike other antipsychotics, aripiprazole is a dopamine D2 partial agonist. In this regard, our results suggest that aripiprazole has numerous advantages, especially in cases of stuporous catatonia and a defective general status.

Authors+Show Affiliations

Department of Child Psychiatry, Chiba University Hospital, Inohana 1-8-1, Chiba, 260-8670, Japan. sasaki@faculty.chiba-u.jp.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports

Language

eng

PubMed ID

22553911

Citation

Sasaki, Tsuyoshi, et al. "Treatment of Refractory Catatonic Schizophrenia With Low Dose Aripiprazole." Annals of General Psychiatry, vol. 11, no. 1, 2012, p. 12.
Sasaki T, Hashimoto T, Niitsu T, et al. Treatment of refractory catatonic schizophrenia with low dose aripiprazole. Annals of general psychiatry. 2012;11(1):12.
Sasaki, T., Hashimoto, T., Niitsu, T., Kanahara, N., & Iyo, M. (2012). Treatment of refractory catatonic schizophrenia with low dose aripiprazole. Annals of General Psychiatry, 11(1), 12. https://doi.org/10.1186/1744-859X-11-12
Sasaki T, et al. Treatment of Refractory Catatonic Schizophrenia With Low Dose Aripiprazole. Annals of general psychiatry. 2012 May 3;11(1):12. PubMed PMID: 22553911.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of refractory catatonic schizophrenia with low dose aripiprazole. AU - Sasaki,Tsuyoshi, AU - Hashimoto,Tasuku, AU - Niitsu,Tomihisa, AU - Kanahara,Nobuhisa, AU - Iyo,Masaomi, Y1 - 2012/05/03/ PY - 2012/02/23/received PY - 2012/04/12/accepted PY - 2012/5/5/entrez PY - 2012/5/5/pubmed PY - 2012/5/5/medline SP - 12 EP - 12 JF - Annals of general psychiatry VL - 11 IS - 1 N2 - This case is of 54-year-old female with catatonic schizophrenia, characterized by treatment resistance to the pharmacotherapy with olanzapine, risperidone, flunitrazepam, and ECT. Olanzapine and risperidone and flunitrazepam did not improve her catatonic and psychotic symptoms, and induced the extrapyramidal symptoms. The effects of ECT did not continue even for a month. However, the treatment with low-dose aripiprazole dramatically improved the patient's psychotic symptoms and extrapyramidal symptoms. The mechanisms underlying the effects of low-dose aripiprazole in this case remain unclear, but unlike other antipsychotics, aripiprazole is a dopamine D2 partial agonist. In this regard, our results suggest that aripiprazole has numerous advantages, especially in cases of stuporous catatonia and a defective general status. SN - 1744-859X UR - https://www.unboundmedicine.com/medline/citation/22553911/Treatment_of_refractory_catatonic_schizophrenia_with_low_dose_aripiprazole_ L2 - https://annals-general-psychiatry.biomedcentral.com/articles/10.1186/1744-859X-11-12 DB - PRIME DP - Unbound Medicine ER -
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