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Lumbar spine radiographic features and demographic, clinical, and radiographic knee, hip, and hand osteoarthritis.
Arthritis Care Res (Hoboken). 2012 Oct; 64(10):1536-44.AC

Abstract

OBJECTIVE

To determine the prevalence of lumbar spine individual radiographic features (IRFs) of disc space narrowing (DSN), osteophytes (OST), and facet joint osteoarthritis (FOA); to describe the frequencies of demographic, clinical, and radiographic knee, hip, and hand osteoarthritis (OA) across lumbar spine IRFs; and to determine factors associated with lumbar spine IRFs.

METHODS

We conducted a cross-sectional study of 840 participants enrolled in the Johnston County Osteoarthritis Project (2003-2004). Sample-based prevalence estimates were generated for each lumbar spine IRF. The associations between lumbar spine IRFs and demographic, clinical, and peripheral joint OA were determined with logistic regression models.

RESULTS

Sample-based prevalence estimates were similar for DSN (57.6%) and FOA (57.9%) but higher for OST (88.1%), with significant differences across race and sex. Hand and knee OA frequencies increased across IRFs, whereas the effect was absent for hip OA. African Americans had lower odds of FOA (adjusted odds ratio [OR(adj) ] 0.45 [95% confidence interval (95% CI) 0.32-0.62]), while there was no racial association with DSN and OST. Low back symptoms were associated with DSN (OR(adj) 1.37 [95% CI 1.04-1.80]) but not OST or FOA. Knee OA was associated with OST (OR(adj) 1.62 [95% CI 1.16-2.27]) and FOA (OR(adj) 1.69 [95% CI 1.15-2.49]) but not DSN. Hand OA was associated with FOA (OR(adj) 1.67 [95% CI 1.20-2.28]) but not with DSN or OST. No associations were found with hip OA.

CONCLUSION

These findings underscore the importance of analyzing lumbar spine IRFs separately as the associations with demographic, clinical, and radiographic knee, hip, and hand OA differ widely.

Authors+Show Affiliations

Duke University, Durham, NC 27708, USA. adam.goode@duke.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

22556059

Citation

Goode, Adam P., et al. "Lumbar Spine Radiographic Features and Demographic, Clinical, and Radiographic Knee, Hip, and Hand Osteoarthritis." Arthritis Care & Research, vol. 64, no. 10, 2012, pp. 1536-44.
Goode AP, Marshall SW, Renner JB, et al. Lumbar spine radiographic features and demographic, clinical, and radiographic knee, hip, and hand osteoarthritis. Arthritis Care Res (Hoboken). 2012;64(10):1536-44.
Goode, A. P., Marshall, S. W., Renner, J. B., Carey, T. S., Kraus, V. B., Irwin, D. E., Stürmer, T., & Jordan, J. M. (2012). Lumbar spine radiographic features and demographic, clinical, and radiographic knee, hip, and hand osteoarthritis. Arthritis Care & Research, 64(10), 1536-44. https://doi.org/10.1002/acr.21720
Goode AP, et al. Lumbar Spine Radiographic Features and Demographic, Clinical, and Radiographic Knee, Hip, and Hand Osteoarthritis. Arthritis Care Res (Hoboken). 2012;64(10):1536-44. PubMed PMID: 22556059.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lumbar spine radiographic features and demographic, clinical, and radiographic knee, hip, and hand osteoarthritis. AU - Goode,Adam P, AU - Marshall,Stephen W, AU - Renner,Jordan B, AU - Carey,Timothy S, AU - Kraus,Virginia B, AU - Irwin,Debra E, AU - Stürmer,Til, AU - Jordan,Joanne M, PY - 2012/5/5/entrez PY - 2012/5/5/pubmed PY - 2013/1/17/medline SP - 1536 EP - 44 JF - Arthritis care & research JO - Arthritis Care Res (Hoboken) VL - 64 IS - 10 N2 - OBJECTIVE: To determine the prevalence of lumbar spine individual radiographic features (IRFs) of disc space narrowing (DSN), osteophytes (OST), and facet joint osteoarthritis (FOA); to describe the frequencies of demographic, clinical, and radiographic knee, hip, and hand osteoarthritis (OA) across lumbar spine IRFs; and to determine factors associated with lumbar spine IRFs. METHODS: We conducted a cross-sectional study of 840 participants enrolled in the Johnston County Osteoarthritis Project (2003-2004). Sample-based prevalence estimates were generated for each lumbar spine IRF. The associations between lumbar spine IRFs and demographic, clinical, and peripheral joint OA were determined with logistic regression models. RESULTS: Sample-based prevalence estimates were similar for DSN (57.6%) and FOA (57.9%) but higher for OST (88.1%), with significant differences across race and sex. Hand and knee OA frequencies increased across IRFs, whereas the effect was absent for hip OA. African Americans had lower odds of FOA (adjusted odds ratio [OR(adj) ] 0.45 [95% confidence interval (95% CI) 0.32-0.62]), while there was no racial association with DSN and OST. Low back symptoms were associated with DSN (OR(adj) 1.37 [95% CI 1.04-1.80]) but not OST or FOA. Knee OA was associated with OST (OR(adj) 1.62 [95% CI 1.16-2.27]) and FOA (OR(adj) 1.69 [95% CI 1.15-2.49]) but not DSN. Hand OA was associated with FOA (OR(adj) 1.67 [95% CI 1.20-2.28]) but not with DSN or OST. No associations were found with hip OA. CONCLUSION: These findings underscore the importance of analyzing lumbar spine IRFs separately as the associations with demographic, clinical, and radiographic knee, hip, and hand OA differ widely. SN - 2151-4658 UR - https://www.unboundmedicine.com/medline/citation/22556059/Lumbar_spine_radiographic_features_and_demographic_clinical_and_radiographic_knee_hip_and_hand_osteoarthritis_ L2 - https://doi.org/10.1002/acr.21720 DB - PRIME DP - Unbound Medicine ER -