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Clinical evaluation of intensity-modulated radiotherapy for head and neck cancers.


Radiotherapy and surgery are the principal curative modalities in treatment of head and neck cancer. Conventional two-dimensional and three-dimensional conformal radiotherapy result in significant side effects and altered quality of life. Intensity-modulated radiotherapy (IMRT) can spare the normal tissues, while delivering a curative dose to the tumour-bearing tissues. This article reviews the current role of IMRT in head and neck cancer from the point of view of normal tissue sparing, and also reviews the current published literature by individual head and neck cancer subsites. In addition, we briefly discuss the role of image guidance in head and neck IMRT, and future directions in this area.


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    Head and Neck Unit, Royal Marsden Hospital, Sutton, Surrey, UK.

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    The British journal of radiology 85:1013 2012 May pg 487-94


    Carcinoma, Squamous Cell
    Deglutition Disorders
    Head and Neck Neoplasms
    Hypopharyngeal Neoplasms
    Laryngeal Neoplasms
    Nasopharyngeal Neoplasms
    Oropharyngeal Neoplasms
    Paranasal Sinus Neoplasms
    Parotid Gland
    Parotid Neoplasms
    Radiation Oncology
    Radiotherapy Planning, Computer-Assisted
    Radiotherapy, Intensity-Modulated
    Thyroid Neoplasms

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't



    PubMed ID