Tags

Type your tag names separated by a space and hit enter

A 1-year randomized controlled trial comparing mind body exercise (Tai Chi) with stretching and toning exercise on cognitive function in older Chinese adults at risk of cognitive decline.
J Am Med Dir Assoc. 2012 Jul; 13(6):568.e15-20.JA

Abstract

OBJECTIVES

To compare the effectiveness of Chinese-style mind-body exercise (24 forms simplified Tai Chi) versus stretching and toning exercise in the maintenance of cognitive abilities in Chinese elders at risk of cognitive decline.

DESIGN

A 1-year single-blind cluster randomized controlled trial.

SETTINGS

Community centers and residential homes for elders in Hong Kong.

PARTICIPANTS

A total of 389 subjects at risk of cognitive decline (Clinical Dementia Rating, CDR 0.5 or amnestic-MCI) participated in an exercise intervention program.

INTERVENTION

A total of 171 subjects were trained with Tai Chi (Intervention [I]) and 218 were trained with stretching and toning exercise (Control [C]).

METHODS

Cognitive and functional performance were assessed at the baseline, and at 5, 9, and 12 months. Data were analyzed using multilevel mixed models. Primary outcomes included progression to clinical dementia as diagnosed by DSM-IV criteria, and change of cognitive and functional scores. Secondary outcomes included postural balance measured by the Berg Balance Scale neuropsychiatric and mood symptoms measured by the Neuropsychiatric Inventory, and Cornell Scale for Depression in Dementia.

RESULTS

At 1 year, 92 (54%) and 169 (78%) participants of the I and C groups completed the intervention. Multilevel logistic regression with completers-only analyses controlled for baseline differences in education revealed that the I group had a trend for lower risk of developing dementia at 1 year (odds ratio 0.21, 95% CI 0.05-0.92, P = .04). The I group had better preservation of CDR sum of boxes scores than the C group in both intention-to-treat (P = .04) and completers-only analyses (P = .004). In completers-only analyses, the I group had greater improvement in delay recall (P = .05) and Cornell Scale for Depression in Dementia scores (P = .02).

CONCLUSION

Regular exercise, especially mind-body exercise with integrated cognitive and motor coordination, may help with preservation of global ability in elders at risk of cognitive decline; however, logistics to promote long-term practice and optimize adherence needs to be revisited.

Authors+Show Affiliations

Department of Psychiatry, the Chinese University of Hong Kong, Hong Kong. cwlam@cuhk.edu.hkNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22579072

Citation

Lam, Linda C W., et al. "A 1-year Randomized Controlled Trial Comparing Mind Body Exercise (Tai Chi) With Stretching and Toning Exercise On Cognitive Function in Older Chinese Adults at Risk of Cognitive Decline." Journal of the American Medical Directors Association, vol. 13, no. 6, 2012, pp. 568.e15-20.
Lam LC, Chau RC, Wong BM, et al. A 1-year randomized controlled trial comparing mind body exercise (Tai Chi) with stretching and toning exercise on cognitive function in older Chinese adults at risk of cognitive decline. J Am Med Dir Assoc. 2012;13(6):568.e15-20.
Lam, L. C., Chau, R. C., Wong, B. M., Fung, A. W., Tam, C. W., Leung, G. T., Kwok, T. C., Leung, T. Y., Ng, S. P., & Chan, W. M. (2012). A 1-year randomized controlled trial comparing mind body exercise (Tai Chi) with stretching and toning exercise on cognitive function in older Chinese adults at risk of cognitive decline. Journal of the American Medical Directors Association, 13(6), e15-20. https://doi.org/10.1016/j.jamda.2012.03.008
Lam LC, et al. A 1-year Randomized Controlled Trial Comparing Mind Body Exercise (Tai Chi) With Stretching and Toning Exercise On Cognitive Function in Older Chinese Adults at Risk of Cognitive Decline. J Am Med Dir Assoc. 2012;13(6):568.e15-20. PubMed PMID: 22579072.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A 1-year randomized controlled trial comparing mind body exercise (Tai Chi) with stretching and toning exercise on cognitive function in older Chinese adults at risk of cognitive decline. AU - Lam,Linda C W, AU - Chau,Rachel C M, AU - Wong,Billy M L, AU - Fung,Ada W T, AU - Tam,Cindy W C, AU - Leung,Grace T Y, AU - Kwok,Timothy C Y, AU - Leung,Tony Y S, AU - Ng,Sammy P, AU - Chan,Wai M, Y1 - 2012/05/11/ PY - 2011/12/21/received PY - 2012/03/28/revised PY - 2012/03/28/accepted PY - 2012/5/15/entrez PY - 2012/5/15/pubmed PY - 2012/12/10/medline SP - 568.e15 EP - 20 JF - Journal of the American Medical Directors Association JO - J Am Med Dir Assoc VL - 13 IS - 6 N2 - OBJECTIVES: To compare the effectiveness of Chinese-style mind-body exercise (24 forms simplified Tai Chi) versus stretching and toning exercise in the maintenance of cognitive abilities in Chinese elders at risk of cognitive decline. DESIGN: A 1-year single-blind cluster randomized controlled trial. SETTINGS: Community centers and residential homes for elders in Hong Kong. PARTICIPANTS: A total of 389 subjects at risk of cognitive decline (Clinical Dementia Rating, CDR 0.5 or amnestic-MCI) participated in an exercise intervention program. INTERVENTION: A total of 171 subjects were trained with Tai Chi (Intervention [I]) and 218 were trained with stretching and toning exercise (Control [C]). METHODS: Cognitive and functional performance were assessed at the baseline, and at 5, 9, and 12 months. Data were analyzed using multilevel mixed models. Primary outcomes included progression to clinical dementia as diagnosed by DSM-IV criteria, and change of cognitive and functional scores. Secondary outcomes included postural balance measured by the Berg Balance Scale neuropsychiatric and mood symptoms measured by the Neuropsychiatric Inventory, and Cornell Scale for Depression in Dementia. RESULTS: At 1 year, 92 (54%) and 169 (78%) participants of the I and C groups completed the intervention. Multilevel logistic regression with completers-only analyses controlled for baseline differences in education revealed that the I group had a trend for lower risk of developing dementia at 1 year (odds ratio 0.21, 95% CI 0.05-0.92, P = .04). The I group had better preservation of CDR sum of boxes scores than the C group in both intention-to-treat (P = .04) and completers-only analyses (P = .004). In completers-only analyses, the I group had greater improvement in delay recall (P = .05) and Cornell Scale for Depression in Dementia scores (P = .02). CONCLUSION: Regular exercise, especially mind-body exercise with integrated cognitive and motor coordination, may help with preservation of global ability in elders at risk of cognitive decline; however, logistics to promote long-term practice and optimize adherence needs to be revisited. SN - 1538-9375 UR - https://www.unboundmedicine.com/medline/citation/22579072/A_1_year_randomized_controlled_trial_comparing_mind_body_exercise__Tai_Chi__with_stretching_and_toning_exercise_on_cognitive_function_in_older_Chinese_adults_at_risk_of_cognitive_decline_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1525-8610(12)00089-8 DB - PRIME DP - Unbound Medicine ER -