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Influence of acute sleep loss on the neural correlates of alerting, orientating and executive attention components.
J Sleep Res 2012; 21(6):648-58JS

Abstract

The Attention Network Test (ANT) is deemed to assess the alerting, orientating and executive components of human attention. Capitalizing on the opportunity to investigate three facets of attention in a single task, we used functional magnetic resonance imaging (fMRI) to assess the effect of sleep deprivation (SD) on brain responses associated with the three attentional components elicited by the ANT. Twelve healthy volunteers were scanned in two conditions 1 week apart, after a normal night of sleep (rested wakefulness, RW) or after one night of total sleep deprivation. Sleep deprivation was associated with a global increase in reaction times, which did not affect specifically any of the three attention effects. Brain responses associated with the alerting effect did not differ between RW and SD. Higher-order attention components (orientating and conflict effects) were associated with significantly larger thalamic responses during SD than during RW. These results suggest that SD influences different components of human attention non-selectively, through mechanisms that might either affect centrencephalic structures maintaining vigilance or ubiquitously perturb neuronal function. Compensatory responses can counter these effects transiently by recruiting thalamic responses, thereby supporting thalamocortical function.

Authors+Show Affiliations

Cyclotron Research Centre, University of Liège, Belgium.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22594455

Citation

Muto, Vincenzo, et al. "Influence of Acute Sleep Loss On the Neural Correlates of Alerting, Orientating and Executive Attention Components." Journal of Sleep Research, vol. 21, no. 6, 2012, pp. 648-58.
Muto V, Shaffii-le Bourdiec A, Matarazzo L, et al. Influence of acute sleep loss on the neural correlates of alerting, orientating and executive attention components. J Sleep Res. 2012;21(6):648-58.
Muto, V., Shaffii-le Bourdiec, A., Matarazzo, L., Foret, A., Mascetti, L., Jaspar, M., ... Maquet, P. (2012). Influence of acute sleep loss on the neural correlates of alerting, orientating and executive attention components. Journal of Sleep Research, 21(6), pp. 648-58. doi:10.1111/j.1365-2869.2012.01020.x.
Muto V, et al. Influence of Acute Sleep Loss On the Neural Correlates of Alerting, Orientating and Executive Attention Components. J Sleep Res. 2012;21(6):648-58. PubMed PMID: 22594455.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influence of acute sleep loss on the neural correlates of alerting, orientating and executive attention components. AU - Muto,Vincenzo, AU - Shaffii-le Bourdiec,Anahita, AU - Matarazzo,Luca, AU - Foret,Ariane, AU - Mascetti,Laura, AU - Jaspar,Mathieu, AU - Vandewalle,Gilles, AU - Phillips,Christophe, AU - Degueldre,Christian, AU - Balteau,Evelyne, AU - Luxen,André, AU - Collette,Fabienne, AU - Maquet,Pierre, Y1 - 2012/05/18/ PY - 2012/5/19/entrez PY - 2012/5/19/pubmed PY - 2013/5/18/medline SP - 648 EP - 58 JF - Journal of sleep research JO - J Sleep Res VL - 21 IS - 6 N2 - The Attention Network Test (ANT) is deemed to assess the alerting, orientating and executive components of human attention. Capitalizing on the opportunity to investigate three facets of attention in a single task, we used functional magnetic resonance imaging (fMRI) to assess the effect of sleep deprivation (SD) on brain responses associated with the three attentional components elicited by the ANT. Twelve healthy volunteers were scanned in two conditions 1 week apart, after a normal night of sleep (rested wakefulness, RW) or after one night of total sleep deprivation. Sleep deprivation was associated with a global increase in reaction times, which did not affect specifically any of the three attention effects. Brain responses associated with the alerting effect did not differ between RW and SD. Higher-order attention components (orientating and conflict effects) were associated with significantly larger thalamic responses during SD than during RW. These results suggest that SD influences different components of human attention non-selectively, through mechanisms that might either affect centrencephalic structures maintaining vigilance or ubiquitously perturb neuronal function. Compensatory responses can counter these effects transiently by recruiting thalamic responses, thereby supporting thalamocortical function. SN - 1365-2869 UR - https://www.unboundmedicine.com/medline/citation/22594455/Influence_of_acute_sleep_loss_on_the_neural_correlates_of_alerting_orientating_and_executive_attention_components_ L2 - https://doi.org/10.1111/j.1365-2869.2012.01020.x DB - PRIME DP - Unbound Medicine ER -