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Melanoma of the sellar region mimicking pituitary adenoma.
Neuropathology. 2013 Apr; 33(2):175-8.N

Abstract

We report here the case of an 82-year-old woman who presented with visual disturbance. MRI demonstrated a sellar mass. The diagnosis of pituitary adenoma was made. She underwent transnasal surgery. Histologic, immunohistochemical and ultrastructural studies indicated that the tumor was a melanoma. Despite an exhaustive search for a primary lesion elsewhere, none was found. The sellar tumor was considered a primary lesion, although extrasellar primary tumor imaging cannot be excluded with 100% certainty. Reported examples of melanoma affecting the sellar region are few. They exhibit morphologic features identical to those of melanomas arising elsewhere. Although very rare, primary melanomas enter into the differential diagnosis of sellar lesions.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Sidiropoulos M
Department of Laboratory Medicine and Pathology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Syro LV
No affiliation info available
Rotondo F
No affiliation info available
Scheithauer BW
No affiliation info available
Penagos LC
No affiliation info available
Uribe H
No affiliation info available
Ramirez Mdel P
No affiliation info available
Horvath E
No affiliation info available
Goth M
No affiliation info available
Kovacs K
No affiliation info available

MeSH

AdenomaAged, 80 and overDiagnosis, DifferentialFemaleHumansMelanomaPituitary NeoplasmsSella TurcicaSkull Neoplasms

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22624497

Citation

Sidiropoulos, Michael, et al. "Melanoma of the Sellar Region Mimicking Pituitary Adenoma." Neuropathology : Official Journal of the Japanese Society of Neuropathology, vol. 33, no. 2, 2013, pp. 175-8.
Sidiropoulos M, Syro LV, Rotondo F, et al. Melanoma of the sellar region mimicking pituitary adenoma. Neuropathology. 2013;33(2):175-8.
Sidiropoulos, M., Syro, L. V., Rotondo, F., Scheithauer, B. W., Penagos, L. C., Uribe, H., Ramirez, M. d. e. l. . P., Horvath, E., Goth, M., & Kovacs, K. (2013). Melanoma of the sellar region mimicking pituitary adenoma. Neuropathology : Official Journal of the Japanese Society of Neuropathology, 33(2), 175-8. https://doi.org/10.1111/j.1440-1789.2012.01331.x
Sidiropoulos M, et al. Melanoma of the Sellar Region Mimicking Pituitary Adenoma. Neuropathology. 2013;33(2):175-8. PubMed PMID: 22624497.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Melanoma of the sellar region mimicking pituitary adenoma. AU - Sidiropoulos,Michael, AU - Syro,Luis V, AU - Rotondo,Fabio, AU - Scheithauer,Bernd W, AU - Penagos,Luis Carlos, AU - Uribe,Humberto, AU - Ramirez,Maria Del Pilar, AU - Horvath,Eva, AU - Goth,Miklos, AU - Kovacs,Kalman, Y1 - 2012/05/25/ PY - 2012/5/26/entrez PY - 2012/5/26/pubmed PY - 2014/2/12/medline SP - 175 EP - 8 JF - Neuropathology : official journal of the Japanese Society of Neuropathology JO - Neuropathology VL - 33 IS - 2 N2 - We report here the case of an 82-year-old woman who presented with visual disturbance. MRI demonstrated a sellar mass. The diagnosis of pituitary adenoma was made. She underwent transnasal surgery. Histologic, immunohistochemical and ultrastructural studies indicated that the tumor was a melanoma. Despite an exhaustive search for a primary lesion elsewhere, none was found. The sellar tumor was considered a primary lesion, although extrasellar primary tumor imaging cannot be excluded with 100% certainty. Reported examples of melanoma affecting the sellar region are few. They exhibit morphologic features identical to those of melanomas arising elsewhere. Although very rare, primary melanomas enter into the differential diagnosis of sellar lesions. SN - 1440-1789 UR - https://www.unboundmedicine.com/medline/citation/22624497/Melanoma_of_the_sellar_region_mimicking_pituitary_adenoma_ DB - PRIME DP - Unbound Medicine ER -