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The treatment of infertility in polycystic ovary syndrome: a brief update.
Aust N Z J Obstet Gynaecol. 2012 Aug; 52(4):400-3.AN

Abstract

Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. Lifestyle change alone is considered the first-line treatment for the management of infertile anovulatory PCOS women who are overweight or obese. First-line medical ovulation induction therapy to improve fertility outcomes is clomiphene citrate, whilst gonadotrophins, laparoscopic ovarian surgery or possibly metformin are second line in clomiphene citrate-resistant PCOS women. There is currently insufficient evidence to recommend aromatase inhibitors over that of clomiphene citrate in infertile anovulatory PCOS women in general or specifically in therapy naive or clomiphene citrate-resistant PCOS women. IVF/ICSI treatment is recommended either as a third-line treatment or in the presence of other infertility factors.

Authors+Show Affiliations

Obstetrics and Gynaecology, University of New South Wales, Sydney, NSW, Australia. mfcostello@unsw.edu.auNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22639834

Citation

Costello, Michael F., et al. "The Treatment of Infertility in Polycystic Ovary Syndrome: a Brief Update." The Australian & New Zealand Journal of Obstetrics & Gynaecology, vol. 52, no. 4, 2012, pp. 400-3.
Costello MF, Misso ML, Wong J, et al. The treatment of infertility in polycystic ovary syndrome: a brief update. Aust N Z J Obstet Gynaecol. 2012;52(4):400-3.
Costello, M. F., Misso, M. L., Wong, J., Hart, R., Rombauts, L., Melder, A., Norman, R. J., & Teede, H. J. (2012). The treatment of infertility in polycystic ovary syndrome: a brief update. The Australian & New Zealand Journal of Obstetrics & Gynaecology, 52(4), 400-3. https://doi.org/10.1111/j.1479-828X.2012.01448.x
Costello MF, et al. The Treatment of Infertility in Polycystic Ovary Syndrome: a Brief Update. Aust N Z J Obstet Gynaecol. 2012;52(4):400-3. PubMed PMID: 22639834.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The treatment of infertility in polycystic ovary syndrome: a brief update. AU - Costello,Michael F, AU - Misso,Marie L, AU - Wong,Jennifer, AU - Hart,Roger, AU - Rombauts,Luk, AU - Melder,Angela, AU - Norman,Robert J, AU - Teede,Helena J, Y1 - 2012/05/28/ PY - 2012/03/08/received PY - 2012/04/06/accepted PY - 2012/5/30/entrez PY - 2012/5/30/pubmed PY - 2012/12/18/medline SP - 400 EP - 3 JF - The Australian & New Zealand journal of obstetrics & gynaecology JO - Aust N Z J Obstet Gynaecol VL - 52 IS - 4 N2 - Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. Lifestyle change alone is considered the first-line treatment for the management of infertile anovulatory PCOS women who are overweight or obese. First-line medical ovulation induction therapy to improve fertility outcomes is clomiphene citrate, whilst gonadotrophins, laparoscopic ovarian surgery or possibly metformin are second line in clomiphene citrate-resistant PCOS women. There is currently insufficient evidence to recommend aromatase inhibitors over that of clomiphene citrate in infertile anovulatory PCOS women in general or specifically in therapy naive or clomiphene citrate-resistant PCOS women. IVF/ICSI treatment is recommended either as a third-line treatment or in the presence of other infertility factors. SN - 1479-828X UR - https://www.unboundmedicine.com/medline/citation/22639834/The_treatment_of_infertility_in_polycystic_ovary_syndrome:_a_brief_update_ DB - PRIME DP - Unbound Medicine ER -