Tags

Type your tag names separated by a space and hit enter

Appetitive-aversive interactions in Pavlovian fear conditioning.
Behav Neurosci. 2012 Jun; 126(3):404-22.BN

Abstract

The existence of value coding and salience coding neurons in the mammalian brain, including in habenula and ventral tegmental area, has sparked considerable interest in the interactions that occur between Pavlovian appetitive and aversive conditioning. Here we studied these appetitive-aversive interactions at the behavioral level by assessing the learning that occurs when a Pavlovian appetitive conditioned stimulus (conditional stimulus, CS) serves as a CS for shock in Pavlovian fear conditioning. A Pavlovian appetitive CS was retarded in the rate at which it could be transformed into a fear CS (counterconditioning), but the presence of the appetitive CS augmented fear learning to a concurrently presented neutral CS (superconditioning). Retardation of fear learning was not alleviated by manipulations designed to restore the associability of the appetitive CS before fear conditioning but was alleviated by manipulations designed to increase the aversive quality of the shock unconditioned stimulus (US). These findings are consistent with opponent interactions between the appetitive and aversive motivational systems and provide a behavioral approach for assessing the neural correlates of these appetitive-aversive interactions.

Authors+Show Affiliations

School of Psychology, The University of New South Wales, Sydney, Australia.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22642885

Citation

Nasser, Helen M., and Gavan P. McNally. "Appetitive-aversive Interactions in Pavlovian Fear Conditioning." Behavioral Neuroscience, vol. 126, no. 3, 2012, pp. 404-22.
Nasser HM, McNally GP. Appetitive-aversive interactions in Pavlovian fear conditioning. Behav Neurosci. 2012;126(3):404-22.
Nasser, H. M., & McNally, G. P. (2012). Appetitive-aversive interactions in Pavlovian fear conditioning. Behavioral Neuroscience, 126(3), 404-22. https://doi.org/10.1037/a0028341
Nasser HM, McNally GP. Appetitive-aversive Interactions in Pavlovian Fear Conditioning. Behav Neurosci. 2012;126(3):404-22. PubMed PMID: 22642885.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Appetitive-aversive interactions in Pavlovian fear conditioning. AU - Nasser,Helen M, AU - McNally,Gavan P, PY - 2012/5/31/entrez PY - 2012/5/31/pubmed PY - 2013/3/26/medline SP - 404 EP - 22 JF - Behavioral neuroscience JO - Behav Neurosci VL - 126 IS - 3 N2 - The existence of value coding and salience coding neurons in the mammalian brain, including in habenula and ventral tegmental area, has sparked considerable interest in the interactions that occur between Pavlovian appetitive and aversive conditioning. Here we studied these appetitive-aversive interactions at the behavioral level by assessing the learning that occurs when a Pavlovian appetitive conditioned stimulus (conditional stimulus, CS) serves as a CS for shock in Pavlovian fear conditioning. A Pavlovian appetitive CS was retarded in the rate at which it could be transformed into a fear CS (counterconditioning), but the presence of the appetitive CS augmented fear learning to a concurrently presented neutral CS (superconditioning). Retardation of fear learning was not alleviated by manipulations designed to restore the associability of the appetitive CS before fear conditioning but was alleviated by manipulations designed to increase the aversive quality of the shock unconditioned stimulus (US). These findings are consistent with opponent interactions between the appetitive and aversive motivational systems and provide a behavioral approach for assessing the neural correlates of these appetitive-aversive interactions. SN - 1939-0084 UR - https://www.unboundmedicine.com/medline/citation/22642885/Appetitive_aversive_interactions_in_Pavlovian_fear_conditioning_ L2 - http://content.apa.org/journals/bne/126/3/404 DB - PRIME DP - Unbound Medicine ER -