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Prenatal and perinatal risk factors of schizophrenia.
J Matern Fetal Neonatal Med 2012; 25(12):2559-63JM

Abstract

Schizophrenia could be considered the most severe of all psychiatric disorders. It shows a heterogeneous clinical picture and presents an etiopathogenesis that is not cleared sufficiently. Even if the etiopathogenesis remains a puzzle, there is a scientific consensus that it is an expression of interaction between genotype and environmental factors. In the present article, following a study of literature and the accumulated evidence, the role of prenatal and perinatal factors in the development of schizophrenia will be revised and synthesized. We think that better knowledge of the risk factors could be helpful not only for better comprehension of the pathogenesis but especially to optimize interventions for prevention of the disorder.

Authors+Show Affiliations

Department of Neuroscience, Institute of Psychiatry, Catholic University of Sacred Heart, Rome, Italy. giampieromeli1@alice.itNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22646662

Citation

Meli, Giampiero, et al. "Prenatal and Perinatal Risk Factors of Schizophrenia." The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 25, no. 12, 2012, pp. 2559-63.
Meli G, Ottl B, Paladini A, et al. Prenatal and perinatal risk factors of schizophrenia. J Matern Fetal Neonatal Med. 2012;25(12):2559-63.
Meli, G., Ottl, B., Paladini, A., & Cataldi, L. (2012). Prenatal and perinatal risk factors of schizophrenia. The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 25(12), pp. 2559-63. doi:10.3109/14767058.2012.699118.
Meli G, et al. Prenatal and Perinatal Risk Factors of Schizophrenia. J Matern Fetal Neonatal Med. 2012;25(12):2559-63. PubMed PMID: 22646662.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prenatal and perinatal risk factors of schizophrenia. AU - Meli,Giampiero, AU - Ottl,Birgit, AU - Paladini,Angela, AU - Cataldi,Luigi, Y1 - 2012/07/18/ PY - 2012/6/1/entrez PY - 2012/6/1/pubmed PY - 2013/6/1/medline SP - 2559 EP - 63 JF - The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians JO - J. Matern. Fetal. Neonatal. Med. VL - 25 IS - 12 N2 - Schizophrenia could be considered the most severe of all psychiatric disorders. It shows a heterogeneous clinical picture and presents an etiopathogenesis that is not cleared sufficiently. Even if the etiopathogenesis remains a puzzle, there is a scientific consensus that it is an expression of interaction between genotype and environmental factors. In the present article, following a study of literature and the accumulated evidence, the role of prenatal and perinatal factors in the development of schizophrenia will be revised and synthesized. We think that better knowledge of the risk factors could be helpful not only for better comprehension of the pathogenesis but especially to optimize interventions for prevention of the disorder. SN - 1476-4954 UR - https://www.unboundmedicine.com/medline/citation/22646662/Prenatal_and_perinatal_risk_factors_of_schizophrenia_ L2 - http://www.tandfonline.com/doi/full/10.3109/14767058.2012.699118 DB - PRIME DP - Unbound Medicine ER -