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Preventing gastric sieving by blending a solid/water meal enhances satiation in healthy humans.
J Nutr. 2012 Jul; 142(7):1253-8.JN

Abstract

Separation of solids and liquids within the stomach allows faster gastric emptying of liquids compared with solids, a phenomenon known as sieving. We tested the hypothesis that blending a solid and water meal would abolish sieving, preventing the early rapid decrease in gastric volume and thereby enhancing satiety. We carried out 2 separate studies. Study 1 was a 2-way, crossover, satiety study of 22 healthy volunteers who consumed roasted chicken and vegetables with a glass of water (1008 kJ) or the same blended to a soup. They completed satiety visual analogue scales at intervals for 3 h. Study 2 was a 2-way, crossover, mechanistic study of 18 volunteers who consumed the same meals and underwent an MRI to assess gastric emptying, gallbladder contraction, and small bowel water content (SBWC) at intervals for 3 h. In Study 1, the soup meal was associated with reduced hunger (P = 0.02). In Study 2, the volume of the gastric contents after the soup meal decreased more slowly than after the solid/liquid meal (P = 0.0003). The soup meal caused greater gallbladder contraction (P < 0.04). SBWC showed a biphasic response with an initial "gastric" phase during which SBWC was greater when the solid/liquid meal was consumed (P < 0.001) and a later "small bowel" phase when SBWC was greater when the soup meal was consumed (P < 0.01). Blending the solid/liquid meal to a soup delayed gastric emptying and increased the hormonal response to feeding, which may contribute to enhanced postprandial satiety.

Authors+Show Affiliations

Nottingham Digestive Diseases Centre and NIHR Biomedical Research Unit, Nottingham University Hospitals, Nottingham, UK.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22649258

Citation

Marciani, Luca, et al. "Preventing Gastric Sieving By Blending a Solid/water Meal Enhances Satiation in Healthy Humans." The Journal of Nutrition, vol. 142, no. 7, 2012, pp. 1253-8.
Marciani L, Hall N, Pritchard SE, et al. Preventing gastric sieving by blending a solid/water meal enhances satiation in healthy humans. J Nutr. 2012;142(7):1253-8.
Marciani, L., Hall, N., Pritchard, S. E., Cox, E. F., Totman, J. J., Lad, M., Hoad, C. L., Foster, T. J., Gowland, P. A., & Spiller, R. C. (2012). Preventing gastric sieving by blending a solid/water meal enhances satiation in healthy humans. The Journal of Nutrition, 142(7), 1253-8. https://doi.org/10.3945/jn.112.159830
Marciani L, et al. Preventing Gastric Sieving By Blending a Solid/water Meal Enhances Satiation in Healthy Humans. J Nutr. 2012;142(7):1253-8. PubMed PMID: 22649258.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Preventing gastric sieving by blending a solid/water meal enhances satiation in healthy humans. AU - Marciani,Luca, AU - Hall,Nicholas, AU - Pritchard,Susan E, AU - Cox,Eleanor F, AU - Totman,John J, AU - Lad,Mita, AU - Hoad,Caroline L, AU - Foster,Tim J, AU - Gowland,Penny A, AU - Spiller,Robin C, Y1 - 2012/05/30/ PY - 2012/6/1/entrez PY - 2012/6/1/pubmed PY - 2012/8/31/medline SP - 1253 EP - 8 JF - The Journal of nutrition JO - J Nutr VL - 142 IS - 7 N2 - Separation of solids and liquids within the stomach allows faster gastric emptying of liquids compared with solids, a phenomenon known as sieving. We tested the hypothesis that blending a solid and water meal would abolish sieving, preventing the early rapid decrease in gastric volume and thereby enhancing satiety. We carried out 2 separate studies. Study 1 was a 2-way, crossover, satiety study of 22 healthy volunteers who consumed roasted chicken and vegetables with a glass of water (1008 kJ) or the same blended to a soup. They completed satiety visual analogue scales at intervals for 3 h. Study 2 was a 2-way, crossover, mechanistic study of 18 volunteers who consumed the same meals and underwent an MRI to assess gastric emptying, gallbladder contraction, and small bowel water content (SBWC) at intervals for 3 h. In Study 1, the soup meal was associated with reduced hunger (P = 0.02). In Study 2, the volume of the gastric contents after the soup meal decreased more slowly than after the solid/liquid meal (P = 0.0003). The soup meal caused greater gallbladder contraction (P < 0.04). SBWC showed a biphasic response with an initial "gastric" phase during which SBWC was greater when the solid/liquid meal was consumed (P < 0.001) and a later "small bowel" phase when SBWC was greater when the soup meal was consumed (P < 0.01). Blending the solid/liquid meal to a soup delayed gastric emptying and increased the hormonal response to feeding, which may contribute to enhanced postprandial satiety. SN - 1541-6100 UR - https://www.unboundmedicine.com/medline/citation/22649258/Preventing_gastric_sieving_by_blending_a_solid/water_meal_enhances_satiation_in_healthy_humans_ L2 - https://academic.oup.com/jn/article-lookup/doi/10.3945/jn.112.159830 DB - PRIME DP - Unbound Medicine ER -