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The pharmacological treatment of acquired nystagmus.
Pract Neurol. 2012 Jun; 12(3):147-53.PN

Abstract

We review the latest literature on the neuropharmacological treatments for acquired nystagmus.Nystagmus may have a significant [corrected] impact on health, yet there is little scientific evidence on which to make firm recommendations for treatment. Acquired pendular nystagmus may respond to gabapentin or memantine; downbeat and upbeat nystagmus to aminopyridines; and periodic alternating nystagmus to baclofen. To improve treatment we need multi-centre, randomised controlled trials using standardised techniques in reporting objective outcomes, with good follow-up duration and careful reporting of side effects.

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Authors+Show Affiliations

Mehta AR
Department of Clinical Neurosciences, Neurology Unit, University of Cambridge, Cambridge, UK.
Kennard C
No affiliation info available

MeSH

AminesAminopyridinesBaclofenCyclohexanecarboxylic AcidsGabapentinHumansMemantineNystagmus, CongenitalNystagmus, PathologicRandomized Controlled Trials as TopicTreatment Outcomegamma-Aminobutyric Acid

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22661344

Citation

Mehta, Arpan R., and Christopher Kennard. "The Pharmacological Treatment of Acquired Nystagmus." Practical Neurology, vol. 12, no. 3, 2012, pp. 147-53.
Mehta AR, Kennard C. The pharmacological treatment of acquired nystagmus. Pract Neurol. 2012;12(3):147-53.
Mehta, A. R., & Kennard, C. (2012). The pharmacological treatment of acquired nystagmus. Practical Neurology, 12(3), 147-53. https://doi.org/10.1136/practneurol-2011-000181
Mehta AR, Kennard C. The Pharmacological Treatment of Acquired Nystagmus. Pract Neurol. 2012;12(3):147-53. PubMed PMID: 22661344.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The pharmacological treatment of acquired nystagmus. AU - Mehta,Arpan R, AU - Kennard,Christopher, PY - 2012/6/5/entrez PY - 2012/6/5/pubmed PY - 2013/4/5/medline SP - 147 EP - 53 JF - Practical neurology JO - Pract Neurol VL - 12 IS - 3 N2 - We review the latest literature on the neuropharmacological treatments for acquired nystagmus.Nystagmus may have a significant [corrected] impact on health, yet there is little scientific evidence on which to make firm recommendations for treatment. Acquired pendular nystagmus may respond to gabapentin or memantine; downbeat and upbeat nystagmus to aminopyridines; and periodic alternating nystagmus to baclofen. To improve treatment we need multi-centre, randomised controlled trials using standardised techniques in reporting objective outcomes, with good follow-up duration and careful reporting of side effects. SN - 1474-7766 UR - https://www.unboundmedicine.com/medline/citation/22661344/The_pharmacological_treatment_of_acquired_nystagmus_ L2 - https://pn.bmj.com/lookup/pmidlookup?view=long&pmid=22661344 DB - PRIME DP - Unbound Medicine ER -