Citation
Caron, Mélanie, et al. "Recent Introduction and Rapid Dissemination of Chikungunya Virus and Dengue Virus Serotype 2 Associated With Human and Mosquito Coinfections in Gabon, Central Africa." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 55, no. 6, 2012, pp. e45-53.
Caron M, Paupy C, Grard G, et al. Recent introduction and rapid dissemination of Chikungunya virus and Dengue virus serotype 2 associated with human and mosquito coinfections in Gabon, central Africa. Clin Infect Dis. 2012;55(6):e45-53.
Caron, M., Paupy, C., Grard, G., Becquart, P., Mombo, I., Nso, B. B., Kassa Kassa, F., Nkoghe, D., & Leroy, E. M. (2012). Recent introduction and rapid dissemination of Chikungunya virus and Dengue virus serotype 2 associated with human and mosquito coinfections in Gabon, central Africa. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 55(6), e45-53. https://doi.org/10.1093/cid/cis530
Caron M, et al. Recent Introduction and Rapid Dissemination of Chikungunya Virus and Dengue Virus Serotype 2 Associated With Human and Mosquito Coinfections in Gabon, Central Africa. Clin Infect Dis. 2012;55(6):e45-53. PubMed PMID: 22670036.
TY - JOUR
T1 - Recent introduction and rapid dissemination of Chikungunya virus and Dengue virus serotype 2 associated with human and mosquito coinfections in Gabon, central Africa.
AU - Caron,Mélanie,
AU - Paupy,Christophe,
AU - Grard,Gilda,
AU - Becquart,Pierre,
AU - Mombo,Illich,
AU - Nso,Branly Bikie Bi,
AU - Kassa Kassa,Fabrice,
AU - Nkoghe,Dieudonné,
AU - Leroy,Eric Maurice,
Y1 - 2012/06/05/
PY - 2012/6/7/entrez
PY - 2012/6/7/pubmed
PY - 2013/1/9/medline
SP - e45
EP - 53
JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
JO - Clin Infect Dis
VL - 55
IS - 6
N2 - BACKGROUND: Chikungunya virus (CHIKV) and Dengue virus serotype 2 (DENV-2) were recently introduced in central Africa, along with Aedes albopictus. Simultaneous outbreaks of CHIKV and DENV-2 have subsequently occurred, in Cameroon in 2006 and Gabon in 2007. METHODS: To study the spread of the 2 viruses, we conducted active surveillance of acute febrile syndromes throughout Gabon between 2007 and 2010. Diagnostic methods included quantitative real-time reverse-transcription polymerase chain reaction, and molecular characterization was based on partial envelope gene sequences. RESULTS: Between 2007 and 2010, 4287 acutely febrile patients were investigated for CHIKV and DENV-2 infections, of whom 1567 were CHIKV-positive, 376 DENV-2-positive, and 37 coinfected. We diagnosed 153 CHIKV and 11 DENV-2 cases in 2008, and 5 CHIKV and 9 DENV-2 cases in 2009. In 2010, CHIKV and DENV-2 caused a second large simultaneous outbreak. Among 2826 acutely febrile patients examined during this outbreak, 1112 were CHIKV-positive, 288 DENV-2-positive, and 28 coinfected. Mosquitoes were collected near the homes of coinfected patients, and 1 Aedes albopictus specimen was found to be positive for both CHIKV and DENV-2. CONCLUSIONS: These findings show the rapid dissemination of CHIKV and DENV-2 within a nonimmune population in a tropical African country, probably facilitated by the spread of Aedes albopictus. This has resulted in major simultaneous outbreaks with numerous coinfections in both human and mosquito.
SN - 1537-6591
UR - https://www.unboundmedicine.com/medline/citation/22670036/Recent_introduction_and_rapid_dissemination_of_Chikungunya_virus_and_Dengue_virus_serotype_2_associated_with_human_and_mosquito_coinfections_in_Gabon_central_Africa_
L2 - https://academic.oup.com/cid/article-lookup/doi/10.1093/cid/cis530
DB - PRIME
DP - Unbound Medicine
ER -