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Stereotactic endoscopic placement of third ventricle catheter for long-term infusion of baclofen in patients with secondary generalized dystonia.
J Neurosurg Pediatr. 2012 Jul; 10(1):30-3.JN

Abstract

Continuous infusion of baclofen is a treatment option for severe generalized dystonia. Catheter insertion within the third ventricle has been described as an alternative to standard intrathecal placement to maximize intracranial concentrations of baclofen. The authors describe their experience with a novel technique for stereotactic endoscopic insertion of baclofen infusion catheters in the third ventricle in 3 patients with severe secondary generalized dystonia. Insertion was successful in all 3 patients, and all of them experienced significant improvement in dystonia scores on the Barry-Albright Dystonia Scale. Follow-up ranged from 5.5 to 7 months (mean 6 months), and no mechanical complications or CSF leaks were observed. The stereotactic endoscopic insertion of a baclofen infusion catheter into the third ventricle appears to be a safe method for continuous intraventricular baclofen infusion in patients with generalized secondary dystonia.

Authors+Show Affiliations

Division of Pediatric Neurosurgery, Department of Neurosurgery, Primary Children’s Medical Center, University of Utah, Salt Lake City, Utah 84113, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22681318

Citation

Bollo, Robert J., et al. "Stereotactic Endoscopic Placement of Third Ventricle Catheter for Long-term Infusion of Baclofen in Patients With Secondary Generalized Dystonia." Journal of Neurosurgery. Pediatrics, vol. 10, no. 1, 2012, pp. 30-3.
Bollo RJ, Gooch JL, Walker ML. Stereotactic endoscopic placement of third ventricle catheter for long-term infusion of baclofen in patients with secondary generalized dystonia. J Neurosurg Pediatr. 2012;10(1):30-3.
Bollo, R. J., Gooch, J. L., & Walker, M. L. (2012). Stereotactic endoscopic placement of third ventricle catheter for long-term infusion of baclofen in patients with secondary generalized dystonia. Journal of Neurosurgery. Pediatrics, 10(1), 30-3. https://doi.org/10.3171/2012.3.PEDS11405
Bollo RJ, Gooch JL, Walker ML. Stereotactic Endoscopic Placement of Third Ventricle Catheter for Long-term Infusion of Baclofen in Patients With Secondary Generalized Dystonia. J Neurosurg Pediatr. 2012;10(1):30-3. PubMed PMID: 22681318.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Stereotactic endoscopic placement of third ventricle catheter for long-term infusion of baclofen in patients with secondary generalized dystonia. AU - Bollo,Robert J, AU - Gooch,Judith L, AU - Walker,Marion L, Y1 - 2012/06/08/ PY - 2012/6/12/entrez PY - 2012/6/12/pubmed PY - 2012/9/11/medline SP - 30 EP - 3 JF - Journal of neurosurgery. Pediatrics JO - J Neurosurg Pediatr VL - 10 IS - 1 N2 - Continuous infusion of baclofen is a treatment option for severe generalized dystonia. Catheter insertion within the third ventricle has been described as an alternative to standard intrathecal placement to maximize intracranial concentrations of baclofen. The authors describe their experience with a novel technique for stereotactic endoscopic insertion of baclofen infusion catheters in the third ventricle in 3 patients with severe secondary generalized dystonia. Insertion was successful in all 3 patients, and all of them experienced significant improvement in dystonia scores on the Barry-Albright Dystonia Scale. Follow-up ranged from 5.5 to 7 months (mean 6 months), and no mechanical complications or CSF leaks were observed. The stereotactic endoscopic insertion of a baclofen infusion catheter into the third ventricle appears to be a safe method for continuous intraventricular baclofen infusion in patients with generalized secondary dystonia. SN - 1933-0715 UR - https://www.unboundmedicine.com/medline/citation/22681318/Stereotactic_endoscopic_placement_of_third_ventricle_catheter_for_long_term_infusion_of_baclofen_in_patients_with_secondary_generalized_dystonia_ L2 - https://thejns.org/doi/10.3171/2012.3.PEDS11405 DB - PRIME DP - Unbound Medicine ER -