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Acute toxicity of Ag and CuO nanoparticle suspensions against Daphnia magna: the importance of their dissolved fraction varying with preparation methods.
J Hazard Mater. 2012 Aug 15; 227-228:301-8.JH

Abstract

A variety of methods to prepare nanoparticle suspensions have been employed for aquatic toxicity tests, although they can influence the dispersion property and subsequent toxicity of nanoparticles. Thus, in this study, we prepared stock suspensions of silver (Ag) and copper oxide (CuO) nanoparticles using different methods and compared their acute toxicity against Daphnia magna. The results showed that the dispersion method, filtration and initial concentration largely affected their toxicity, when the toxicity was expressed as the total concentrations of Ag and Cu. In case of Ag nanoparticles, the toxicity was also influenced by their different particle size. However, negligible differences in 24h-median effect concentration (EC(50)) values, which were calculated in terms of their dissolved concentrations, were observed. When expressing toxicity on the basis of dissolved concentrations, 24h-EC(50) values of the Ag and CuO nanoparticles were also found to be similar to those of the counterpart ionic species, i.e., Ag (as AgNO(3)) and Cu (as CuCl(2)·2H(2)O). These findings indicate that the dissolved fraction of nanoparticles largely contributes to their acute toxicity. Our results may help in establishing a useful guideline for preparing nanoparticle suspensions with reproducible toxicity.

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Authors+Show Affiliations

Jo HJ
Water Research Center, Korea Institute of Science and Technology, Seongbuk-gu, Seoul, Republic of Korea.
Choi JW
No affiliation info available
Lee SH
No affiliation info available
Hong SW
No affiliation info available

MeSH

AnimalsCopperDaphniaMetal NanoparticlesParticle SizeSilverSolubilitySuspensionsToxicity Tests, AcuteWater Pollutants, Chemical

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22682800

Citation

Jo, Hun Je, et al. "Acute Toxicity of Ag and CuO Nanoparticle Suspensions Against Daphnia Magna: the Importance of Their Dissolved Fraction Varying With Preparation Methods." Journal of Hazardous Materials, vol. 227-228, 2012, pp. 301-8.
Jo HJ, Choi JW, Lee SH, et al. Acute toxicity of Ag and CuO nanoparticle suspensions against Daphnia magna: the importance of their dissolved fraction varying with preparation methods. J Hazard Mater. 2012;227-228:301-8.
Jo, H. J., Choi, J. W., Lee, S. H., & Hong, S. W. (2012). Acute toxicity of Ag and CuO nanoparticle suspensions against Daphnia magna: the importance of their dissolved fraction varying with preparation methods. Journal of Hazardous Materials, 227-228, 301-8. https://doi.org/10.1016/j.jhazmat.2012.05.066
Jo HJ, et al. Acute Toxicity of Ag and CuO Nanoparticle Suspensions Against Daphnia Magna: the Importance of Their Dissolved Fraction Varying With Preparation Methods. J Hazard Mater. 2012 Aug 15;227-228:301-8. PubMed PMID: 22682800.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute toxicity of Ag and CuO nanoparticle suspensions against Daphnia magna: the importance of their dissolved fraction varying with preparation methods. AU - Jo,Hun Je, AU - Choi,Jae Woo, AU - Lee,Sang Hyup, AU - Hong,Seok Won, Y1 - 2012/05/27/ PY - 2012/01/12/received PY - 2012/05/07/revised PY - 2012/05/18/accepted PY - 2012/6/12/entrez PY - 2012/6/12/pubmed PY - 2012/10/26/medline SP - 301 EP - 8 JF - Journal of hazardous materials JO - J Hazard Mater VL - 227-228 N2 - A variety of methods to prepare nanoparticle suspensions have been employed for aquatic toxicity tests, although they can influence the dispersion property and subsequent toxicity of nanoparticles. Thus, in this study, we prepared stock suspensions of silver (Ag) and copper oxide (CuO) nanoparticles using different methods and compared their acute toxicity against Daphnia magna. The results showed that the dispersion method, filtration and initial concentration largely affected their toxicity, when the toxicity was expressed as the total concentrations of Ag and Cu. In case of Ag nanoparticles, the toxicity was also influenced by their different particle size. However, negligible differences in 24h-median effect concentration (EC(50)) values, which were calculated in terms of their dissolved concentrations, were observed. When expressing toxicity on the basis of dissolved concentrations, 24h-EC(50) values of the Ag and CuO nanoparticles were also found to be similar to those of the counterpart ionic species, i.e., Ag (as AgNO(3)) and Cu (as CuCl(2)·2H(2)O). These findings indicate that the dissolved fraction of nanoparticles largely contributes to their acute toxicity. Our results may help in establishing a useful guideline for preparing nanoparticle suspensions with reproducible toxicity. SN - 1873-3336 UR - https://www.unboundmedicine.com/medline/citation/22682800/Acute_toxicity_of_Ag_and_CuO_nanoparticle_suspensions_against_Daphnia_magna:_the_importance_of_their_dissolved_fraction_varying_with_preparation_methods_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0304-3894(12)00569-9 DB - PRIME DP - Unbound Medicine ER -