Tags

Type your tag names separated by a space and hit enter

Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin.
Biosens Bioelectron. 2012 Oct-Dec; 38(1):163-9.BB

Abstract

A molecularly imprinted electrochemical sensor was fabricated based on gold electrode decorated by chitosan-platinum nanoparticles (CS-PtNPs) and graphene-gold nanoparticles (GR-AuNPs) nanocomposites for convenient and sensitive determination of erythromycin. The synergistic effects of CS-PtNPs and GR-AuNPs nanocomposites improved the electrochemical response and the sensitivity of the sensor. The molecularly imprinted polymers (MIPs) were prepared by HAuCl(4), 2-mercaptonicotinic acid (MNA) and erythromycin. Erythromycin and MNA were used as template molecule and functional monomer, respectively. They were first assembled on the surface of GR-AuNPs/CS-PtNPs/gold electrode by the formation of Au-S bonds and hydrogen-bonding interactions. Then the MIPs were formed by electropolymerization of HAuCl(4), MNA and erythromycin. The sensor was characterized by cyclic voltammetry (CV), scanning electron microscope (SEM), UV-visible (UV-vis) absorption speactra and amperometry. The linear range of the sensor was from 7.0 × 10(-8)mol/L-9.0 × 10(-5)mol/L, with the limit of detection (LOD) of 2.3 × 10(-8)mol/L (S/N=3). The sensor showed high selectivity, excellent stability and good reproducibility for the determination of erythromycin, and it was successfully applied to the detection of erythromycin in real spiked samples.

Authors+Show Affiliations

Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan, Shandong 250022, PR China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22683249

Citation

Lian, Wenjing, et al. "Electrochemical Sensor Based On Gold Nanoparticles Fabricated Molecularly Imprinted Polymer Film at Chitosan-platinum Nanoparticles/graphene-gold Nanoparticles Double Nanocomposites Modified Electrode for Detection of Erythromycin." Biosensors & Bioelectronics, vol. 38, no. 1, 2012, pp. 163-9.
Lian W, Liu S, Yu J, et al. Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. Biosens Bioelectron. 2012;38(1):163-9.
Lian, W., Liu, S., Yu, J., Xing, X., Li, J., Cui, M., & Huang, J. (2012). Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. Biosensors & Bioelectronics, 38(1), 163-9. https://doi.org/10.1016/j.bios.2012.05.017
Lian W, et al. Electrochemical Sensor Based On Gold Nanoparticles Fabricated Molecularly Imprinted Polymer Film at Chitosan-platinum Nanoparticles/graphene-gold Nanoparticles Double Nanocomposites Modified Electrode for Detection of Erythromycin. Biosens Bioelectron. 2012 Oct-Dec;38(1):163-9. PubMed PMID: 22683249.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. AU - Lian,Wenjing, AU - Liu,Su, AU - Yu,Jinghua, AU - Xing,Xianrong, AU - Li,Jie, AU - Cui,Min, AU - Huang,Jiadong, Y1 - 2012/05/24/ PY - 2012/02/27/received PY - 2012/05/08/revised PY - 2012/05/15/accepted PY - 2012/6/12/entrez PY - 2012/6/12/pubmed PY - 2012/12/12/medline SP - 163 EP - 9 JF - Biosensors & bioelectronics JO - Biosens Bioelectron VL - 38 IS - 1 N2 - A molecularly imprinted electrochemical sensor was fabricated based on gold electrode decorated by chitosan-platinum nanoparticles (CS-PtNPs) and graphene-gold nanoparticles (GR-AuNPs) nanocomposites for convenient and sensitive determination of erythromycin. The synergistic effects of CS-PtNPs and GR-AuNPs nanocomposites improved the electrochemical response and the sensitivity of the sensor. The molecularly imprinted polymers (MIPs) were prepared by HAuCl(4), 2-mercaptonicotinic acid (MNA) and erythromycin. Erythromycin and MNA were used as template molecule and functional monomer, respectively. They were first assembled on the surface of GR-AuNPs/CS-PtNPs/gold electrode by the formation of Au-S bonds and hydrogen-bonding interactions. Then the MIPs were formed by electropolymerization of HAuCl(4), MNA and erythromycin. The sensor was characterized by cyclic voltammetry (CV), scanning electron microscope (SEM), UV-visible (UV-vis) absorption speactra and amperometry. The linear range of the sensor was from 7.0 × 10(-8)mol/L-9.0 × 10(-5)mol/L, with the limit of detection (LOD) of 2.3 × 10(-8)mol/L (S/N=3). The sensor showed high selectivity, excellent stability and good reproducibility for the determination of erythromycin, and it was successfully applied to the detection of erythromycin in real spiked samples. SN - 1873-4235 UR - https://www.unboundmedicine.com/medline/citation/22683249/Electrochemical_sensor_based_on_gold_nanoparticles_fabricated_molecularly_imprinted_polymer_film_at_chitosan_platinum_nanoparticles/graphene_gold_nanoparticles_double_nanocomposites_modified_electrode_for_detection_of_erythromycin_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0956-5663(12)00310-7 DB - PRIME DP - Unbound Medicine ER -