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Probiotics and Helicobacter pylori infection in children.
J Biol Regul Homeost Agents 2012 Jan-Mar; 26(1 Suppl):S69-76JB

Abstract

Approximately 50 percent of the world population is infected with Helicobacter pylori (H. pylori), with the highest prevalence rates in developing countries. The current guidelines suggest the use of triple therapy as first choice treatment of Helicobacter pylori infection, although the eradication failure rate is more than 30 percent. Current interest in probiotics as therapeutic agents against Helicobacter pylori is stimulated by the increasing resistance of pathogenic bacteria to antibiotics, thus the interest for alternative therapies is a real actual topic. Available data in children indicate that probiotics seem to be efficacious for the prevention of antibiotic associated side-effects, and might be of help for the prevention of Helicobacter pylori complications by decreasing Helicobacter pylori density and gastritis, and for the prevention of Helicobacter pylori colonization or re-infection by inhibiting adhesion to gastric epithelial cells. There is no clear evidence that probiotics may increase the Helicobacter pylori eradication rate.

Authors+Show Affiliations

Department of Pediatrics, University of Catania, 95125-Catania, Italy. elenalionetti@inwind.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22691253

Citation

Lionetti, E, et al. "Probiotics and Helicobacter Pylori Infection in Children." Journal of Biological Regulators and Homeostatic Agents, vol. 26, no. 1 Suppl, 2012, pp. S69-76.
Lionetti E, Francavilla R, Castellazzi AM, et al. Probiotics and Helicobacter pylori infection in children. J Biol Regul Homeost Agents. 2012;26(1 Suppl):S69-76.
Lionetti, E., Francavilla, R., Castellazzi, A. M., Arrigo, T., Labò, E., Leonardi, S., ... La Rosa, M. (2012). Probiotics and Helicobacter pylori infection in children. Journal of Biological Regulators and Homeostatic Agents, 26(1 Suppl), pp. S69-76.
Lionetti E, et al. Probiotics and Helicobacter Pylori Infection in Children. J Biol Regul Homeost Agents. 2012;26(1 Suppl):S69-76. PubMed PMID: 22691253.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Probiotics and Helicobacter pylori infection in children. AU - Lionetti,E, AU - Francavilla,R, AU - Castellazzi,A M, AU - Arrigo,T, AU - Labò,E, AU - Leonardi,S, AU - Ciprandi,G, AU - Miraglia Del Giudice,M, AU - Salpietro,V, AU - Salpietro,C, AU - La Rosa,M, PY - 2012/6/14/entrez PY - 2013/1/11/pubmed PY - 2013/4/24/medline SP - S69 EP - 76 JF - Journal of biological regulators and homeostatic agents JO - J. Biol. Regul. Homeost. Agents VL - 26 IS - 1 Suppl N2 - Approximately 50 percent of the world population is infected with Helicobacter pylori (H. pylori), with the highest prevalence rates in developing countries. The current guidelines suggest the use of triple therapy as first choice treatment of Helicobacter pylori infection, although the eradication failure rate is more than 30 percent. Current interest in probiotics as therapeutic agents against Helicobacter pylori is stimulated by the increasing resistance of pathogenic bacteria to antibiotics, thus the interest for alternative therapies is a real actual topic. Available data in children indicate that probiotics seem to be efficacious for the prevention of antibiotic associated side-effects, and might be of help for the prevention of Helicobacter pylori complications by decreasing Helicobacter pylori density and gastritis, and for the prevention of Helicobacter pylori colonization or re-infection by inhibiting adhesion to gastric epithelial cells. There is no clear evidence that probiotics may increase the Helicobacter pylori eradication rate. SN - 0393-974X UR - https://www.unboundmedicine.com/medline/citation/22691253/Probiotics_and_Helicobacter_pylori_infection_in_children_ L2 - https://medlineplus.gov/helicobacterpyloriinfections.html DB - PRIME DP - Unbound Medicine ER -