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Vitamin K-dependent multifactor coagulopathy in Devon Rex cats.
J Am Vet Med Assoc 1990; 197(11):1495-7JA

Abstract

A coagulopathy attributable to a deficiency of vitamin K-dependent clotting factors (II, VII, IX, and X) was diagnosed in 3 Devon Rex cats. There was no evidence for exposure to vitamin-antagonist-related rodenticides. The cats did not have evidence of hepatic disease, gastrointestinal disease, or fat malassimilation. Oral treatment with vitamin K1 resulted in normalization of clotting factor concentrations. However, when treatment was discontinued in 2 cats, prothrombin and activated partial thromboplastin values became prolonged again, although the cats did not have clinical signs of a bleeding disorder.

Authors+Show Affiliations

Department of Veterinary Clinical Sciences, University of Sydney, N.S.W., Australia.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

2272883

Citation

Maddison, J E., et al. "Vitamin K-dependent Multifactor Coagulopathy in Devon Rex Cats." Journal of the American Veterinary Medical Association, vol. 197, no. 11, 1990, pp. 1495-7.
Maddison JE, Watson AD, Eade IG, et al. Vitamin K-dependent multifactor coagulopathy in Devon Rex cats. J Am Vet Med Assoc. 1990;197(11):1495-7.
Maddison, J. E., Watson, A. D., Eade, I. G., & Exner, T. (1990). Vitamin K-dependent multifactor coagulopathy in Devon Rex cats. Journal of the American Veterinary Medical Association, 197(11), pp. 1495-7.
Maddison JE, et al. Vitamin K-dependent Multifactor Coagulopathy in Devon Rex Cats. J Am Vet Med Assoc. 1990 Dec 1;197(11):1495-7. PubMed PMID: 2272883.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vitamin K-dependent multifactor coagulopathy in Devon Rex cats. AU - Maddison,J E, AU - Watson,A D, AU - Eade,I G, AU - Exner,T, PY - 1990/12/1/pubmed PY - 1990/12/1/medline PY - 1990/12/1/entrez SP - 1495 EP - 7 JF - Journal of the American Veterinary Medical Association JO - J. Am. Vet. Med. Assoc. VL - 197 IS - 11 N2 - A coagulopathy attributable to a deficiency of vitamin K-dependent clotting factors (II, VII, IX, and X) was diagnosed in 3 Devon Rex cats. There was no evidence for exposure to vitamin-antagonist-related rodenticides. The cats did not have evidence of hepatic disease, gastrointestinal disease, or fat malassimilation. Oral treatment with vitamin K1 resulted in normalization of clotting factor concentrations. However, when treatment was discontinued in 2 cats, prothrombin and activated partial thromboplastin values became prolonged again, although the cats did not have clinical signs of a bleeding disorder. SN - 0003-1488 UR - https://www.unboundmedicine.com/medline/citation/2272883/Vitamin_K_dependent_multifactor_coagulopathy_in_Devon_Rex_cats_ L2 - https://medlineplus.gov/bleedingdisorders.html DB - PRIME DP - Unbound Medicine ER -