Tags

Type your tag names separated by a space and hit enter

Heart healthy diet and risk of myocardial infarction and venous thromboembolism. The Tromsø Study.
Thromb Haemost 2012; 108(3):554-60TH

Abstract

Prudent dietary patterns are associated with reduced risk of arterial cardiovascular diseases (CVD). Limited data exist on the relation between diet and venous thromboembolism (VTE). The aim of our prospective, population based study was to investigate the association of a heart healthy diet on risk of myocardial infarction (MI) and VTE. Information on dietary habits was available in 18,062 subjects, aged 25-69, who participated in the fourth Tromsø study, 1994-1995. Dietary patterns were assessed by a slightly modified version of the validated SmartDiet score; a 13-item questionnaire producing a diet score based on the intakes of fat, fibre, fruit and vegetables. Incident events of MI (n=518) and VTE (n=172) were recorded to the end of follow-up December 31, 2005 (median follow-up 10.8 years). Cox-regression models were used to calculate hazard ratios (HR). A healthy diet score of >27 points (upper tertile) was associated with 17% reduced risk of MI (HR: 0.83, 95% confidence interval [CI]: 0.66-1.06), and no association with VTE (HR: 1.01; 95%CI: 0.66-1.56), compared to <24 points (lower tertile) in multivariable analysis. High intake of fish, fruit, vegetables and polyunsatured fat had a 23% reduced risk of MI (HR 0.77; 95%CI: 0.60-0.98), but no association with VTE (HR 0.95; 95%CI: 0.64-1.40). A heart healthy diet showed an even more favourable association with MI in obese subjects (HR: 0.62; 95%CI: 0.41-0.95), but not with VTE. Our findings suggest that a heart healthy dietary pattern is associated with moderately reduced risk of MI, but not related to risk of VTE.

Authors+Show Affiliations

Hematological Research Group, Department of Clinical Sciences, University of Tromsø, Tromsø, Norway. ida.j.hansen-krone@uit.noNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22739999

Citation

Hansen-Krone, Ida J., et al. "Heart Healthy Diet and Risk of Myocardial Infarction and Venous Thromboembolism. the Tromsø Study." Thrombosis and Haemostasis, vol. 108, no. 3, 2012, pp. 554-60.
Hansen-Krone IJ, Enga KF, Njølstad I, et al. Heart healthy diet and risk of myocardial infarction and venous thromboembolism. The Tromsø Study. Thromb Haemost. 2012;108(3):554-60.
Hansen-Krone, I. J., Enga, K. F., Njølstad, I., Hansen, J. B., & Braekkan, S. K. (2012). Heart healthy diet and risk of myocardial infarction and venous thromboembolism. The Tromsø Study. Thrombosis and Haemostasis, 108(3), pp. 554-60. doi:10.1160/TH11-11-0818.
Hansen-Krone IJ, et al. Heart Healthy Diet and Risk of Myocardial Infarction and Venous Thromboembolism. the Tromsø Study. Thromb Haemost. 2012;108(3):554-60. PubMed PMID: 22739999.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Heart healthy diet and risk of myocardial infarction and venous thromboembolism. The Tromsø Study. AU - Hansen-Krone,Ida J, AU - Enga,Kristin F, AU - Njølstad,Inger, AU - Hansen,John-Bjarne, AU - Braekkan,Sigrid K, Y1 - 2012/06/28/ PY - 2011/11/29/received PY - 2012/05/19/accepted PY - 2012/6/29/entrez PY - 2012/6/29/pubmed PY - 2013/2/15/medline SP - 554 EP - 60 JF - Thrombosis and haemostasis JO - Thromb. Haemost. VL - 108 IS - 3 N2 - Prudent dietary patterns are associated with reduced risk of arterial cardiovascular diseases (CVD). Limited data exist on the relation between diet and venous thromboembolism (VTE). The aim of our prospective, population based study was to investigate the association of a heart healthy diet on risk of myocardial infarction (MI) and VTE. Information on dietary habits was available in 18,062 subjects, aged 25-69, who participated in the fourth Tromsø study, 1994-1995. Dietary patterns were assessed by a slightly modified version of the validated SmartDiet score; a 13-item questionnaire producing a diet score based on the intakes of fat, fibre, fruit and vegetables. Incident events of MI (n=518) and VTE (n=172) were recorded to the end of follow-up December 31, 2005 (median follow-up 10.8 years). Cox-regression models were used to calculate hazard ratios (HR). A healthy diet score of >27 points (upper tertile) was associated with 17% reduced risk of MI (HR: 0.83, 95% confidence interval [CI]: 0.66-1.06), and no association with VTE (HR: 1.01; 95%CI: 0.66-1.56), compared to <24 points (lower tertile) in multivariable analysis. High intake of fish, fruit, vegetables and polyunsatured fat had a 23% reduced risk of MI (HR 0.77; 95%CI: 0.60-0.98), but no association with VTE (HR 0.95; 95%CI: 0.64-1.40). A heart healthy diet showed an even more favourable association with MI in obese subjects (HR: 0.62; 95%CI: 0.41-0.95), but not with VTE. Our findings suggest that a heart healthy dietary pattern is associated with moderately reduced risk of MI, but not related to risk of VTE. SN - 2567-689X UR - https://www.unboundmedicine.com/medline/citation/22739999/Heart_healthy_diet_and_risk_of_myocardial_infarction_and_venous_thromboembolism__The_Tromsø_Study_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1160/TH11-11-0818 DB - PRIME DP - Unbound Medicine ER -