Prime

Type your tag names separated by a space and hit enter

Asymmetric hydroalkynylation of norbornadienes promoted by chiral iridium catalysts.

Abstract

Across bonds: The first successful iridium-catalyzed asymmetric hydroalkynylation of nonpolar alkenes with good to excellent enantioselectivity is described (see scheme; cod = 1,5-cyclooctadiene, DCE = 1,2-dichloroethane). This catalytic system exhibits good functional group compatibility as NH(2), OH, Br, F, and SiMe(3) groups remain intact during the reaction.

Links

  • Publisher Full Text
  • Authors

    , , , , , , , ,

    Source

    MeSH

    Alkynes
    Bridged Compounds
    Catalysis
    Iridium
    Molecular Structure
    Norbornanes
    Organometallic Compounds
    Stereoisomerism

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    22744889