Tags

Type your tag names separated by a space and hit enter

Comparison of the after-effects of transcranial direct current stimulation over the motor cortex in patients with stroke and healthy volunteers.
Int J Neurosci 2012; 122(11):675-81IJ

Abstract

It is known that weak transcranial direct current stimulation (tDCS) induces persistent excitability changes in the cerebral cortex. There are, however, few studies that compare the after-effects of anodal versus cathodal tDCS in patients with stroke. This study assessed the after-effects of tDCS over the motor cortex in patients with hemiparetic stroke and healthy volunteers. Seven stroke patients and nine healthy volunteers were recruited. Ten minutes of anodal and cathodal tDCS (1 mA) and sham stimulation were applied to the affected primary motor cortex (M1) on different days. In healthy subjects, tDCS was applied to the right M1. Before and after tDCS, motor-evoked potentials (MEPs) in the first dorsal interosseous (FDI) muscle and silent period were measured. Anodal tDCS increased the MEPs of the affected FDI in patients with stroke as well as in healthy subjects. Cathodal tDCS increased the MEPs of the affected FDI in patients with stroke. In healthy subjects, however, cathodal tDCS decreased the MEPs. We found no significant change in the duration of the silent period after anodal or cathodal tDCS. We found that both anodal and cathodal tDCS increased the affected M1 excitability in patients with stroke. It is thought that the after-effects of tDCS are different in patients with stroke compared with healthy subjects.

Authors+Show Affiliations

Department of Rehabilitation Medicine, Keio University School of Medicine, Tokyo, Japan. kanjiro6@eco.ocn.ne.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22747238

Citation

Suzuki, Kanjiro, et al. "Comparison of the After-effects of Transcranial Direct Current Stimulation Over the Motor Cortex in Patients With Stroke and Healthy Volunteers." The International Journal of Neuroscience, vol. 122, no. 11, 2012, pp. 675-81.
Suzuki K, Fujiwara T, Tanaka N, et al. Comparison of the after-effects of transcranial direct current stimulation over the motor cortex in patients with stroke and healthy volunteers. Int J Neurosci. 2012;122(11):675-81.
Suzuki, K., Fujiwara, T., Tanaka, N., Tsuji, T., Masakado, Y., Hase, K., ... Liu, M. (2012). Comparison of the after-effects of transcranial direct current stimulation over the motor cortex in patients with stroke and healthy volunteers. The International Journal of Neuroscience, 122(11), pp. 675-81. doi:10.3109/00207454.2012.707715.
Suzuki K, et al. Comparison of the After-effects of Transcranial Direct Current Stimulation Over the Motor Cortex in Patients With Stroke and Healthy Volunteers. Int J Neurosci. 2012;122(11):675-81. PubMed PMID: 22747238.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of the after-effects of transcranial direct current stimulation over the motor cortex in patients with stroke and healthy volunteers. AU - Suzuki,Kanjiro, AU - Fujiwara,Toshiyuki, AU - Tanaka,Naofumi, AU - Tsuji,Tetsuya, AU - Masakado,Yoshihisa, AU - Hase,Kimitaka, AU - Kimura,Akio, AU - Liu,Meigen, Y1 - 2012/08/02/ PY - 2012/7/4/entrez PY - 2012/7/4/pubmed PY - 2013/3/21/medline SP - 675 EP - 81 JF - The International journal of neuroscience JO - Int. J. Neurosci. VL - 122 IS - 11 N2 - It is known that weak transcranial direct current stimulation (tDCS) induces persistent excitability changes in the cerebral cortex. There are, however, few studies that compare the after-effects of anodal versus cathodal tDCS in patients with stroke. This study assessed the after-effects of tDCS over the motor cortex in patients with hemiparetic stroke and healthy volunteers. Seven stroke patients and nine healthy volunteers were recruited. Ten minutes of anodal and cathodal tDCS (1 mA) and sham stimulation were applied to the affected primary motor cortex (M1) on different days. In healthy subjects, tDCS was applied to the right M1. Before and after tDCS, motor-evoked potentials (MEPs) in the first dorsal interosseous (FDI) muscle and silent period were measured. Anodal tDCS increased the MEPs of the affected FDI in patients with stroke as well as in healthy subjects. Cathodal tDCS increased the MEPs of the affected FDI in patients with stroke. In healthy subjects, however, cathodal tDCS decreased the MEPs. We found no significant change in the duration of the silent period after anodal or cathodal tDCS. We found that both anodal and cathodal tDCS increased the affected M1 excitability in patients with stroke. It is thought that the after-effects of tDCS are different in patients with stroke compared with healthy subjects. SN - 1563-5279 UR - https://www.unboundmedicine.com/medline/citation/22747238/Comparison_of_the_after_effects_of_transcranial_direct_current_stimulation_over_the_motor_cortex_in_patients_with_stroke_and_healthy_volunteers_ L2 - http://www.tandfonline.com/doi/full/10.3109/00207454.2012.707715 DB - PRIME DP - Unbound Medicine ER -