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Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method.
Acta Pharm. 2012 Jun; 62(2):191-200.AP

Abstract

Accurate and sensitive methods were developed for simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium in their binary mixtures, and in the presence of a methocarbamol related substance (guaifenesin) using mean centering of the ratio spectra method. The results obtained were statistically compared with the reported HPLC methods; no significant difference between the proposed methods and the reported methods was found regarding either accuracy or precision.

Links

Publisher Full Text
degruyter.com
degruyter.com

Authors+Show Affiliations

Ali NW
Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt. dr.nourali@hotmail.com
Hegazy MA
No affiliation info available
Abdelkawy M
No affiliation info available
Abdelaleem EA
No affiliation info available

MeSH

Anti-Inflammatory Agents, Non-SteroidalCalibrationChromatography, High Pressure LiquidComputing MethodologiesDiclofenacDrug CombinationsDrug StabilityExpectorantsGuaifenesinIbuprofenLimit of DetectionMethocarbamolMuscle Relaxants, CentralReproducibility of ResultsSpectrophotometry, UltravioletTabletsTechnology, Pharmaceutical

Pub Type(s)

Journal Article
Validation Study

Language

eng

PubMed ID

22750817

Citation

Ali, Nouruddin Wageih, et al. "Simultaneous Determination of Methocarbamol and Ibuprofen or Diclofenac Potassium Using Mean Centering of the Ratio Spectra Method." Acta Pharmaceutica (Zagreb, Croatia), vol. 62, no. 2, 2012, pp. 191-200.
Ali NW, Hegazy MA, Abdelkawy M, et al. Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method. Acta Pharm. 2012;62(2):191-200.
Ali, N. W., Hegazy, M. A., Abdelkawy, M., & Abdelaleem, E. A. (2012). Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method. Acta Pharmaceutica (Zagreb, Croatia), 62(2), 191-200. https://doi.org/10.2478/v10007-012-0016-z
Ali NW, et al. Simultaneous Determination of Methocarbamol and Ibuprofen or Diclofenac Potassium Using Mean Centering of the Ratio Spectra Method. Acta Pharm. 2012;62(2):191-200. PubMed PMID: 22750817.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method. AU - Ali,Nouruddin Wageih, AU - Hegazy,Maha Ahamd, AU - Abdelkawy,Mohamed, AU - Abdelaleem,Eglal Abdelahamid, PY - 2012/7/4/entrez PY - 2012/7/4/pubmed PY - 2012/10/31/medline SP - 191 EP - 200 JF - Acta pharmaceutica (Zagreb, Croatia) JO - Acta Pharm VL - 62 IS - 2 N2 - Accurate and sensitive methods were developed for simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium in their binary mixtures, and in the presence of a methocarbamol related substance (guaifenesin) using mean centering of the ratio spectra method. The results obtained were statistically compared with the reported HPLC methods; no significant difference between the proposed methods and the reported methods was found regarding either accuracy or precision. SN - 1846-9558 UR - https://www.unboundmedicine.com/medline/citation/22750817/Simultaneous_determination_of_methocarbamol_and_ibuprofen_or_diclofenac_potassium_using_mean_centering_of_the_ratio_spectra_method_ L2 - https://www.degruyter.com/document/doi/10.2478/v10007-012-0016-z DB - PRIME DP - Unbound Medicine ER -